Phosphamidon

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Phosphamidon

File:(E,Z)-Phosphamidon Structural Formulae V.1.svg
Names
IUPAC name (E/Z)-[3-Chloro-4-(diethylamino)-4-oxobut-2-en-2-yl] dimethyl phosphate
Other names Dimecron
Identifiers
CAS Number	13171-21-6
3D model (JSmol)	Interactive image
ECHA InfoCard
KEGG	C18689 Y
PubChem CID	25750
UNII	7H857A6N6H Y
SMILES CCN(CC)C(=O)C(=C(C)OP(=O)(OC)OC)Cl
Properties
Chemical formula	C10H19ClNO5P
Molar mass	299.69 g·mol−1
Hazards
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

WikiDoc Resources for Phosphamidon
Articles
Most recent articles on Phosphamidon Most cited articles on Phosphamidon Review articles on Phosphamidon Articles on Phosphamidon in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Phosphamidon Images of Phosphamidon Photos of Phosphamidon Podcasts & MP3s on Phosphamidon Videos on Phosphamidon
Evidence Based Medicine
Cochrane Collaboration on Phosphamidon Bandolier on Phosphamidon TRIP on Phosphamidon
Clinical Trials
Ongoing Trials on Phosphamidon at Clinical Trials.gov Trial results on Phosphamidon Clinical Trials on Phosphamidon at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Phosphamidon NICE Guidance on Phosphamidon NHS PRODIGY Guidance FDA on Phosphamidon CDC on Phosphamidon
Books
Books on Phosphamidon
News
Phosphamidon in the news Be alerted to news on Phosphamidon News trends on Phosphamidon
Commentary
Blogs on Phosphamidon
Definitions
Definitions of Phosphamidon
Patient Resources / Community
Patient resources on Phosphamidon Discussion groups on Phosphamidon Patient Handouts on Phosphamidon Directions to Hospitals Treating Phosphamidon Risk calculators and risk factors for Phosphamidon
Healthcare Provider Resources
Symptoms of Phosphamidon Causes & Risk Factors for Phosphamidon Diagnostic studies for Phosphamidon Treatment of Phosphamidon
Continuing Medical Education (CME)
CME Programs on Phosphamidon
International
Phosphamidon en Espanol Phosphamidon en Francais
Business
Phosphamidon in the Marketplace Patents on Phosphamidon
Experimental / Informatics
List of terms related to Phosphamidon

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Phosphamidon is an organophosphate insecticide first reported in 1960. It acts as a cholinesterase inhibitor.

The commercial product typically exists as a mixture of 70% (Z)-isomer and 30% (E)-isomer.

Toxicity and regulation

Phosphamidon is very highly toxic to mammals and is listed as WHO Hazard Class Ia. A harvester developed symptoms of moderately severe poisoning after working in a field that had been sprayed with the chemical 2 weeks earlier. He collapsed and exhibited significant depression of serum cholinesterase, but recovered completely within 2 days after successful treatment with atropine. International trade of phosphamidon is covered by the Rotterdam Convention.