Aortic stenosis symptoms: Difference between revisions
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*[[Sensation of feeling the heart beat]] ([[palpitations]]). | *[[Sensation of feeling the heart beat]] ([[palpitations]]). | ||
====Symptoms in Infants and | ====Symptoms in Infants and Children:==== | ||
*Becoming tired or [[fatigue]]d with exertion more easily than others (in mild cases) | *Becoming tired or [[fatigue]]d with exertion more easily than others (in mild cases) | ||
*Serious [[breathing problems]] that develop within days or weeks of birth (in severe cases) | *Serious [[breathing problems]] that develop within days or weeks of birth (in severe cases) | ||
Revision as of 15:15, 29 November 2012
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Aortic Stenosis Microchapters |
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Diagnosis |
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Treatment |
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Percutaneous Aortic Balloon Valvotomy (PABV) or Aortic Valvuloplasty |
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Transcatheter Aortic Valve Replacement (TAVR) |
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Case Studies |
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Aortic stenosis symptoms On the Web |
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American Roentgen Ray Society Images of Aortic stenosis symptoms |
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Risk calculators and risk factors for Aortic stenosis symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Mohammed A. Sbeih, M.D. [2]; Lakshmi Gopalakrishnan, M.B.B.S. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]
Overview
The main symptoms of aortic stenosis are angina, syncope and congestive heart failure. Left untreated, the average survival is 5 years after the onset of angina, 3 years after the onset of syncope, and 1 year after the onset of congestive heart failure [1][2][3]. Other symptoms of aortic stenosis are dyspnea on exertion, orthopnea and paroxysmal nocturnal dyspnea.
Symptoms
Symptoms in Adults:
- Breathlessness with activity.
- Chest pain, which resembles what is known as angina-type pain.
- The pain is crushing, squeezing, pressure or tightness in nature.
- The pain increases with exercise, relieved with rest.
- The patient feels pain under the chest bone, it may move to other areas.
- Fainting, weakness, or dizziness with activity.
- Sensation of feeling the heart beat (palpitations).
Symptoms in Infants and Children:
- Becoming tired or fatigued with exertion more easily than others (in mild cases)
- Serious breathing problems that develop within days or weeks of birth (in severe cases)
- Extremely tired
- Sweaty
- Pale skin
- Fast breathing
- They may also be smaller than other children their age
Children with mild or moderate aortic stenosis may get worse as the get older. They also run the risk of developing an infection of the heart valves (bacterial endocarditis).
Angina Pectoris
- The hypertrophied left ventricle and the prolonged ejection time (the time for the heart to eject blood) result in an increased myocardial oxygen requirements. The elevated diastolic filling pressure also reduces the gradient between the aorta and the right atrium ("the height of the waterfall") which normally drives coronary blood flow. The hypertrophied ventricle may also compress the capillaries. All of the above reasons lead to a reduction in coronary blood flow even in the absence of obstructive epicardial stenoses. This may result in subendocardial ischemia during stress or exercise.[4][5].
- Left untreated, the average survival is 5 years after the onset of angina in the patient with aortic stenosis.
Syncope
The mechanism of syncope secondary to aortic stenosis remains unclear. Left untreated, the average survival is 3 years after the onset of syncope in the patient with aortic stenosis. Three theroeis have been hypothesized to explain the relationship between aortic stenosis and syncope.
- Severe aortic stenosis results in a nearly fixed cardiac output:
- During exercise, the peripheral vascular resistance will decrease as the blood vessels dilate to allow the skeletal muscles to receive more blood. This decrease in peripheral vascular resistance is normally compensated by an increase in the cardiac output. Since patients with severe aortic stenosis cannot increase their cardiac output, the blood pressure falls and the patient will develop syncope due to decreased blood flow to the brain.
- During exercise, the high pressures generated by the hypertrophied left ventricle can result in a secondary peripheral vasodilation and decreased overall blood flow to the brain:
- During exercise, the high pressures generated in the hypertrophied left ventricle may cause a vasodepressor response, which subsequently results in peripheral vasodilation. As a consequence, the blood flow to the brain may decrease. Therefore, due to the fixed outwards blood flow obstruction at the level of the stenosed aortic valve, it may be impossible for the heart to increase its output to offset the peripheral vasodilation.
- Left ventricular hypertrophy may result in a decrement in the functional integrity of the coronary arteries and the blood flow may be inadequate to supply the walls of the myocardium resulting in syncope
- Syncope can occur in patients with aortic stenosis secondary to myocardial ischemia. Myocardial ischemia can develop in patients with aortic stenosis due to the hypertrophy of the left ventricle and the subsequent inability of the coronary arteries to adequately supply blood to the myocardium.
Congestive Heart Failure
CHF in the setting of aortic stenosis is due to a combination of systolic dysfunction (a decrease in the ejection fraction) and diastolic dysfunction (elevated filling pressure of the left ventricle). Left untreated, the average survival is 5 years after the onset of angina, 3 years after the onset of syncope, and 1 year after the onset of congestive heart failure [1][2][3].
Symptoms of left ventricular failure include the following:
- Dyspnea on exertion
- Fatigue
- Orthopnea
- Paroxysmal nocturnal dyspnea
- Pulmonary edema
- Pulmonary hypertension that can lead to:
Associated Conditions
Heyde's Syndrome
- In Heyde's syndrome, aortic stenosis is associated with angiodysplasia of the colon.
- Presenting symptoms include: hematemesis, melena
Von Willebrand Disease
- Aortic stenosis may result in a form of von Willebrand disease due to an increased turbulence around the stenosed aortic valve which subsequently triggers the break down of coagulation factor VIII-associated antigen, (also called von Willebrand factor) and thus results in a variant of von Willebrand disease.
References
- ↑ 1.0 1.1 Ross J, Braunwald E (1968). "Aortic stenosis". Circulation. 38 (1 Suppl): 61–7. PMID 4894151.
- ↑ 2.0 2.1 Kelly TA, Rothbart RM, Cooper CM, Kaiser DL, Smucker ML, Gibson RS (1988). "Comparison of outcome of asymptomatic to symptomatic patients older than 20 years of age with valvular aortic stenosis". Am J Cardiol. 61 (1): 123–30. PMID 3337000.
- ↑ 3.0 3.1 Iivanainen AM, Lindroos M, Tilvis R, Heikkilä J, Kupari M (1996). "Natural history of aortic valve stenosis of varying severity in the elderly". Am J Cardiol. 78 (1): 97–101. PMID 8712130.
- ↑ Marcus ML, Doty DB, Hiratzka LF, Wright CB, Eastham CL (1982). "Decreased coronary reserve: a mechanism for angina pectoris in patients with aortic stenosis and normal coronary arteries". N Engl J Med. 307 (22): 1362–6. doi:10.1056/NEJM198211253072202. PMID 6215582.
- ↑ Carabello BA (2002). "Clinical practice. Aortic stenosis". N Engl J Med. 346 (9): 677–82. doi:10.1056/NEJMcp010846. PMID 11870246.