Mitral regurgitation differential diagnosis: Difference between revisions

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==Common Causes of Mitral Regurgitation==
==Common Causes of Mitral Regurgitation==
===Chronic Mitral Regurgitation===
===Chronic Mitral Regurgitation===
*Developed World: [[Mitral valve prolapse]] ([[MVP]]), which caused by [[myxomatous degeneration]].<ref name='MedicineNetMVP-Kulick'>{{cite web|url=http://www.medicinenet.com/mitral_valve_prolapse/article.htm |title=Mitral Valve Prolapse (MVP) |accessdate=2010-01-18 |last=Kulick |first=Daniel |work=MedicineNet.com |publisher=MedicineNet, Inc }}</ref>   
*'''Developed World:''' [[Mitral valve prolapse]] ([[MVP]]).<ref name='MedicineNetMVP-Kulick'>{{cite web|url=http://www.medicinenet.com/mitral_valve_prolapse/article.htm |title=Mitral Valve Prolapse (MVP) |accessdate=2010-01-18 |last=Kulick |first=Daniel |work=MedicineNet.com |publisher=MedicineNet, Inc }}</ref>   
*Developing World: [[Rheumatic heart disease]]
*'''Developing World:''' [[Rheumatic heart disease]]
* [[Ischemic heart disease]] causes mitral regurgitation by the combination of ischemic dysfunction of the [[papillary muscles]], the abnormal motion of the underlying wall, and the dilatation of the [[left ventricle]] that is present in ischemic heart disease, with the subsequent displacement of the papillary muscles and the dilatation of the [[mitral valve]] annulus.
* [[Ischemic heart disease]] causes mitral regurgitation by the combination of ischemic dysfunction of the [[papillary muscles]], the abnormal motion of the underlying wall, and the dilatation of the [[left ventricle]] that is present in ischemic heart disease, with the subsequent displacement of the papillary muscles and the dilatation of the [[mitral valve]] annulus.
*[[Marfan's syndrome]] <ref name=agabegi2nd-ch1/>
*[[Marfan's syndrome]] <ref name=agabegi2nd-ch1/>
*Secondary mitral regurgitation due to the dilatation of the [[left ventricle]], caused by stretching of the mitral valve annulus and displacement of the papillary muscles.  This dilatation of the left ventricle can be due to any cause of [[dilated cardiomyopathy]], including [[aortic insufficiency]], nonischemic dilated [[cardiomyopathy]] and [[Noncompaction Cardiomyopathy]]. It is also called '''functional mitral regurgitation''', because the papillary muscles, chordae, and valve leaflets are usually normal.<ref>[http://www.uptodate.com/patients/content/topic.do?topicKey=~Ux3kbGWsXmiaqiH Functional mitral regurgitation] By William H Gaasch, MD. Retrieved on Jul 8, 2010</ref>
*Secondary mitral regurgitation due to the dilatation of the [[left ventricle]], caused by stretching of the mitral valve annulus and displacement of the papillary muscles.  This dilatation of the left ventricle can be due to any cause of [[dilated cardiomyopathy]], including [[aortic insufficiency]], nonischemic dilated [[cardiomyopathy]] and [[Noncompaction Cardiomyopathy]]. It is also called '''functional mitral regurgitation''', because the papillary muscles, chordae, and valve leaflets are usually normal.<ref>[http://www.uptodate.com/patients/content/topic.do?topicKey=~Ux3kbGWsXmiaqiH Functional mitral regurgitation] By William H Gaasch, MD. Retrieved on Jul 8, 2010</ref>
===Acute Mitral Regurgitation===
===Acute Mitral Regurgitation===
*Acute bacterial [[endocarditis]]. The predominant organism is ''[[Staphylococcus aureus|S. aureus]]'', but varies depending upon the patient.<ref name=agabegi2nd-ch1>{{cite book |author=Elizabeth D Agabegi; Agabegi, Steven S. |title=Step-Up to Medicine (Step-Up Series) |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2008 |pages= |isbn=0-7817-7153-6 |oclc= |doi= |accessdate=}}  Chapter 1: Diseases of the Cardiovascular system > Section: Valvular Heart Disease</ref>
*Acute bacterial [[endocarditis]]. The predominant organism is ''[[Staphylococcus aureus|S. aureus]]'', but varies depending upon the patient.<ref name=agabegi2nd-ch1>{{cite book |author=Elizabeth D Agabegi; Agabegi, Steven S. |title=Step-Up to Medicine (Step-Up Series) |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2008 |pages= |isbn=0-7817-7153-6 |oclc= |doi= |accessdate=}}  Chapter 1: Diseases of the Cardiovascular system > Section: Valvular Heart Disease</ref>

Revision as of 23:45, 26 February 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Common Causes of Mitral Regurgitation

Chronic Mitral Regurgitation

Acute Mitral Regurgitation

Full Differential Diagnosis of Causes of Mitral Regurgitaion

Listed alphabetically:

Complete Differential Diagnosis of the Causes of Mitral Regurgitation

(By organ system)

Cardiovascular | Cardiomyopathy | Coronary Heart Disease |Congenital mitral regurgitation | Dilation of Mitral annulus due to Heart Failure | Hypertrophic obstructive cardiomyopathy | Infective endocarditis | Left ventricular dilation | Mitral annular calcification | Mitral valve prolapse | Myocardial Infarction | Myocardial ischemia | Myxomatous degeneration | Prosthetic valve dysfunction
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Ehlers-Danlos Syndrome | Marfan Syndrome | Osteogenesis imperfecta
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease Endocarditis most often due to Staphylococcus aureus [2] | Syphilis
Musculoskeletal / Ortho Infective endocarditis
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Amyloid | Ehlers-Danlos Syndrome Rheumatic Heart Disease | Systemic Lupus Erythematosus
Sexual No underlying causes
Trauma Trauma and motor vehicle accident
Urologic No underlying causes
Miscellaneous No underlying causes

References

  1. Kulick, Daniel. "Mitral Valve Prolapse (MVP)". MedicineNet.com. MedicineNet, Inc. Retrieved 2010-01-18.
  2. 2.0 2.1 2.2 2.3 Elizabeth D Agabegi; Agabegi, Steven S. (2008). Step-Up to Medicine (Step-Up Series). Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-7153-6. Chapter 1: Diseases of the Cardiovascular system > Section: Valvular Heart Disease
  3. Functional mitral regurgitation By William H Gaasch, MD. Retrieved on Jul 8, 2010
  4. British Medical Journal case reports; doi:10.1136/bcr.08.2008.0821

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