Hairy cell leukemia differential diagnosis: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
No edit summary
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Hairy cell leukemia}}
{{Hairy cell leukemia}}
{{CMG}} {{AE}}{{HL}}
==Overview==
* Chronic lymphocytic leukemia must be differentiated from other diseases that cause [[weight loss]],  [[night sweats]], [[hepatosplenomegaly]], and palpable [[lymph node]]s, such as [[hairy cell leukaemia]], prolymphocytic leukaemia, [[follicular lymphoma]], and [[mantle cell lymphoma]].<ref name="H">Hoffbrand V, Moss P. Essential Haematology. John Wiley & Sons; 2011</ref>


Please help WikiDoc by adding content here. It's easy! Click  [[Help:How_to_Edit_a_Page|here]] to learn about editing.
==Differenting Chronic lymphocytic leukemia from other Diseases==
* Chronic lymphocytic leukemia must be differentiated from other diseases that cause [[weight loss]],  [[night sweats]], [[hepatosplenomegaly]], and palpable [[lymph node]]s, such as [[hairy cell leukaemia]], prolymphocytic leukaemia, [[follicular lymphoma]], and [[mantle cell lymphoma]].
* Based on the expression of cell surface markers, the table below differentiates chronic lymphocytic leukemia from other diseases that cause similar clinical presentations:<ref name="H">Hoffbrand V, Moss P. Essential Haematology. John Wiley & Sons; 2011</ref>
<br>
{| style="border: 0px; font-size: 90%; margin: 3px; width: 1000px"
|valign=top|
|+
! style="background: #4479BA; width: 600px;" | {{fontcolor|#FFF|'''Differential Diagnosis'''}}
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''Surface Immunoglobulin'''}}
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''CD5'''}}
! style="background: #4479BA; width: 400px;" | {{fontcolor|#FFF|'''CD22/FMC7'''}}
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''CD23'''}}
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''CD79b'''}}
! style="background: #4479BA; width: 300px;" | {{fontcolor|#FFF|'''CD103'''}}
 
|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
'''Chronic lymphocytic leukaemia'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
'''Weakly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive/Negative'''
 
|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
'''Prolymphocytic leukaemia'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Strongly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
 
|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
'''Hairy cell leukaemia'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Strongly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive/Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
 
|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
'''Mantle cell lymphoma'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Strongly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Strongly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
 
|-
 
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
'''Follicular lymphoma'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Strongly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Strongly positive'''
| style="padding: 5px 5px; background: #F5F5F5;" align=center|
'''Negative'''
|}
<br>
* Chronic lymphocytic leukemia must also be differentiated from other causes of fever, hepatosplenomegaly, and lymph node swelling such as:<ref name="wiki">Chronic Lymphocytic Leukimea. Wikipedia (2015) https://en.wikipedia.org/wiki/B-cell_chronic_lymphocytic_leukemia Accessed on October ,12 2015</ref>
:* [[Splenic marginal zone lymphoma]]
:* Nodal marginal zone [[lymphoma]]
:* [[Lymphoplasmacytic lymphoma]]
:* [[Sézary syndrome]]
:* Smoldering [[adult T cell leukemia]]


==References==
==References==

Revision as of 11:15, 21 October 2015

Hairy cell leukemia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hairy cell leukemia from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Hairy cell leukemia differential diagnosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Hairy cell leukemia differential diagnosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Hairy cell leukemia differential diagnosis

CDC on Hairy cell leukemia differential diagnosis

Hairy cell leukemia differential diagnosis in the news

Blogs on Hairy cell leukemia differential diagnosis

Directions to Hospitals Treating Hairy cell leukemia

Risk calculators and risk factors for Hairy cell leukemia differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Differenting Chronic lymphocytic leukemia from other Diseases
Differential Diagnosis Surface Immunoglobulin CD5 CD22/FMC7 CD23 CD79b CD103

Chronic lymphocytic leukaemia

Weakly positive

Positive

Negative

Positive

Negative

Positive/Negative

Prolymphocytic leukaemia

Strongly positive

Negative

Positive

Negative

Positive

Negative

Hairy cell leukaemia

Strongly positive

Negative

Positive

Negative

Positive/Negative

Positive

Mantle cell lymphoma

Positive

Positive

Strongly positive

Negative

Strongly positive

Negative

Follicular lymphoma

Strongly positive

Negative

Positive

Negative

Strongly positive

Negative


  • Chronic lymphocytic leukemia must also be differentiated from other causes of fever, hepatosplenomegaly, and lymph node swelling such as:[2]

References

  1. ↑ 1.0 1.1 Hoffbrand V, Moss P. Essential Haematology. John Wiley & Sons; 2011
  2. ↑ Chronic Lymphocytic Leukimea. Wikipedia (2015) https://en.wikipedia.org/wiki/B-cell_chronic_lymphocytic_leukemia Accessed on October ,12 2015


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Hairy_cell_leukemia_differential_diagnosis&oldid=1177822"