Sandbox ID Skin and Soft Tissues: Difference between revisions

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:* Preferred regimen (1): [[Amoxicillin-clavulanate]] 875/125 mg PO bid (Some gram-negative rods are resistant; misses MRSA)
:* Preferred regimen (1): [[Amoxicillin-clavulanate]] 875/125 mg PO bid (Some gram-negative rods are resistant; misses MRSA)
:* Preferred regimen (2): [[Ampicillin-sulbactam]]  1.5–3.0 g IV every 6–8 h (Some gram-negative rods are resistant; misses MRSA)
:* Preferred regimen (2): [[Ampicillin-sulbactam]]  1.5–3.0 g IV every 6–8 h (Some gram-negative rods are resistant; misses MRSA)
:* Preferred regimen (3): [[Piperacillin-tazobactam]] 3.37 g IV every 6–8 h (Misses MRSA)
:* Preferred regimen (4): [[Doxycycline]] 100 mg PO bid {{or}} 100 mg IV every 12 h (Excellent activity against Pasteurella multocida; some streptococci are resistant)
:* Preferred regimen (5): [[Penicillin]] {{and}} [[dicloxacillin]] 500 mg oral
:* Preferred regimen (6): [[SMX-TMP]] 160–800 mg PO bid {{or}} IV 5–10 mg/kg/day of TMP component (Good activity against aerobes; poor activity against anaerobes)
:* Preferred regimen (7): [[Metronidazole]]250–500 mg PO tid {{or}} 500 mg IV every 8 h (Good activity against anaerobes; no activity against aerobes)
:* Preferred regimen (8): [[Clindamycin]]300 mg PO tid {{or}} 600 mg IV every 6–8 h (Good activity against staphylococci, streptococci, and anaerobes; misses P. multocida)
:* Preferred regimen (9): [[Cefuroxime]] 500 mg PO bid {{or}} 1 g IV every 12 h
:* Preferred regimen (10): [[Cefoxitin]] 1g IV every 6–8 h
:* Preferred regimen (11): [[Ceftriaxone]] 1g IV every 12 h
:* Preferred regimen (12): [[Cefotaxime]] 1–2 g IV every 6–8 h
:* Preferred regimen (12): [[Ciprofloxacin]] 500–750 mg PO bid {{or}} 400 mg IV every 12 h
:* Preferred regimen (12): [[Levofloxacin]] 750 mg PO daily {{or}} 750 mg IV daily
:* Preferred regimen (12): [[Moxifloxacin]] 400 mg PO daily {{or}} 400 mg IV daily (Monotherapy; good for anaerobes also)





Revision as of 17:35, 26 May 2015

  • Animal bite
  • Preferred regimen (1): Amoxicillin-clavulanate 875/125 mg PO bid (Some gram-negative rods are resistant; misses MRSA)
  • Preferred regimen (2): Ampicillin-sulbactam 1.5–3.0 g IV every 6–8 h (Some gram-negative rods are resistant; misses MRSA)
  • Preferred regimen (3): Piperacillin-tazobactam 3.37 g IV every 6–8 h (Misses MRSA)
  • Preferred regimen (4): Doxycycline 100 mg PO bid OR 100 mg IV every 12 h (Excellent activity against Pasteurella multocida; some streptococci are resistant)
  • Preferred regimen (5): Penicillin AND dicloxacillin 500 mg oral
  • Preferred regimen (6): SMX-TMP 160–800 mg PO bid OR IV 5–10 mg/kg/day of TMP component (Good activity against aerobes; poor activity against anaerobes)
  • Preferred regimen (7): Metronidazole250–500 mg PO tid OR 500 mg IV every 8 h (Good activity against anaerobes; no activity against aerobes)
  • Preferred regimen (8): Clindamycin300 mg PO tid OR 600 mg IV every 6–8 h (Good activity against staphylococci, streptococci, and anaerobes; misses P. multocida)
  • Preferred regimen (9): Cefuroxime 500 mg PO bid OR 1 g IV every 12 h
  • Preferred regimen (10): Cefoxitin 1g IV every 6–8 h
  • Preferred regimen (12): Cefotaxime 1–2 g IV every 6–8 h
  • Preferred regimen (12): Ciprofloxacin 500–750 mg PO bid OR 400 mg IV every 12 h
  • Preferred regimen (12): Levofloxacin 750 mg PO daily OR 750 mg IV daily
  • Preferred regimen (12): Moxifloxacin 400 mg PO daily OR 400 mg IV daily (Monotherapy; good for anaerobes also)



  • Human bite








  • Preferred regimen (1): (Penicillin Voral 500 mg 4 times daily (qid) for 7–10 days
  • Preferred regimen (2): (Ciprofloxacin 500 mg by mouth (po) bid OR levofloxacin 500 mg intravenously (IV)/po every 24 hours × 60 days is recommended for bioterrorism cases because of presumed aerosol exposure

  • Patients >45 kg: 500 mg on day 1 followed by 250 mg for 4 additional days
  • Patients <45 kg: 10 mg/kg on day 1 and 5 mg/kg for 4 more days
  • Preferred regimen (2): (erythromycin 500 mg by mouth (po) qid OR doxycycline 100 mg bid orally for 2 weeks to 2 months




  • Preferred regimen (1): (streptomycin (15 mg/kg every 12 hours IM) OR gentamicin (1.5 mg/kg every 8 hours IV)
  • Preferred regimen (2): (tetracycline (500 mg qid) OR doxycycline (100 mg bid po) is recommended for treatment of mild cases of tularemia

  • Mastitis
  • Breast Implant
  • Non-puerpural mastitis
  • Postpartum mastitis

  • Abscess
  • Boils
  • Furuncles
  • Furunculosis, recurrent
  • Pilonidal cyst
  • Paronychia
  • Acne
  • Rosacea
  • Acne vulgaris
  • Cutaneous anthrax
  • Bacillary angiomatosis
  • Bullous or vesicular lesions
  • Bullous impetigo
  • Chickenpox
  • Hemorrhagic
  • Herpes simplex
  • Herpes zoster
  • Shingles
  • Staphylococcal scalded skin syndrome
  • Varicella
  • Vibro species
  • Cellulitis
  • Cellulitis in diabetic patients
  • Erysipelas
  • Facial cellulitis
  • Cellulitis in non-diabetic patients
  • Orbital cellulitis
  • Cellulitis caused by Vibro species
  • Burns
  • Non-infected wound
  • Infected wound
  • Erythema nodosum
  • Superficial infections
  • Ecthyma
  • Impetigo, crusted
  • Impetigo, bullous
  • Folliculitis
  • Seborrheic dermatitis
  • Lyme disease
  • Lyme disease, Early
  • Lyme disease, Post-exposure prophylaxis
  • Lyme disease, Post-lyme disease syndrome
  • Ecthyma contagiosum
  • Erythrasma
  • Vascular insufficieny ulcers
  • Wound infections
  • Post-operative, negative Gram-stain
  • Post-operative, positive Gram-stain
  • Post-trauma
  • Yaws