Cytomegalovirus infection history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
Presentation of patients with [[Cytomegalovirus infection|CMV infection]] differs with the organ system involved and is as follows: <ref name="urlwww.idsociety.org">{{cite web |url=https://www.idsociety.org/uploadedFiles/HIVMA/Guidelines_Patient_Care/HIVMA_Standards_Practice_Guidelines/HIV_Guidelines/Guidelines_Content/adult_oi.pdf |title=www.idsociety.org |format= |work= |accessdate=}}</ref> | Presentation of patients with [[Cytomegalovirus infection|CMV infection]] differs with the organ system involved and is as follows: <ref name="urlwww.idsociety.org">{{cite web |url=https://www.idsociety.org/uploadedFiles/HIVMA/Guidelines_Patient_Care/HIVMA_Standards_Practice_Guidelines/HIV_Guidelines/Guidelines_Content/adult_oi.pdf |title=www.idsociety.org |format= |work= |accessdate=}}</ref><ref name="pmid27252178">{{cite journal| author=Pinninti S, Hough-Telford C, Pati S, Boppana S| title=Cytomegalovirus and Epstein-Barr Virus Infections. | journal=Pediatr Rev | year= 2016 | volume= 37 | issue= 6 | pages= 223-34 | pmid=27252178 | doi=10.1542/pir.2015-0072 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27252178 }} </ref> | ||
===CMV Retintis=== | ===CMV Retintis=== | ||
*Peripheral [[retinitis]] can be asymptomatic or present with the following symptoms: | *Peripheral [[retinitis]] can be asymptomatic or present with the following symptoms: | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]
Overview
Primary infection in majority of patients have a mononucleosis like presentation. Patients with immunosuppression have symptoms related to the affected organ system. Retinitis presents with blurred vision and floaters. Colitis presents with abdominal pain and bloody diarrhea. Pneumonitis is usually asymptomatic. Neurologic infection presents with altered mental status and focal neurological deficits.
History and Symptoms
Presentation of patients with CMV infection differs with the organ system involved and is as follows: [1][2]
CMV Retintis
- Peripheral retinitis can be asymptomatic or present with the following symptoms:
- Floaters
- Scotomata
- Peripheral visual field defects
- Central retinal lesions or lesions impinging on the macula or optic nerve are result in decreased visual acuity and central field defects.
CMV Colitis
Colitis presents with the following symptoms:
- Weight loss
- Anorexia
- Abdominal pain
- Diarrhea
- Fever
- Malaise
- Patients with perforation of the bowel present with acute abdominal pain.
CMV Esophagitis
Patients with cytomegalovirus esophagitis present with symptoms of:
- Odynophagia
- Nausea
- Mid-epigastric or retrosternal discomfort
- Fever
CMV Encephalitis
Patients with cytomegalovirus encephalitis presents with:
CMV Ventriculoencephalitis
Patients with cytomegalovirus ventricluloencephalitis present:
- Acute onset of symptoms with focal neurological deficits
- Cranial nerve palsies
- Nystagmus
- Rapid progression to death
CMV Polyradiculomyelopathy
Patients with cytomegalovirus polyradiculomyelopathy present with features similar to Guillian Barre Syndrome and have symptoms such as:
- Bladder incontinence
- Paraplegia with gradual worsening of symptoms over weeks
References
- ↑ "www.idsociety.org" (PDF).
- ↑ Pinninti S, Hough-Telford C, Pati S, Boppana S (2016). "Cytomegalovirus and Epstein-Barr Virus Infections". Pediatr Rev. 37 (6): 223–34. doi:10.1542/pir.2015-0072. PMID 27252178.