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* In 1912, Dr. von Hansemann reported five cases with lung interstitial abnormalities in the histologic examination. Dr. von Hansemann named those cases as "lymphangitis reticularis pulmonum".  
* In 1912, Dr. von Hansemann reported five cases with lung interstitial abnormalities in the histologic examination. Dr. von Hansemann named those cases as "lymphangitis reticularis pulmonum".  
* From 1933 to 1944, Hamman and Rich described some cases of IPF. Dr. Hamman and Rich described the clinical and pathological features of a lung disease at which they named it as "acute diffuse interstitial fibrosis of the lungs". The clinical features included dyspnea, cyanosis, and cough. The histological features included alveolar edema, erythrocytosis, and hyalinization.<ref name="pmid13492895">{{cite journal| author=RUBIN EH, LUBLINER R| title=The Hamman-Rich syndrome: review of the literature and analysis of 15 cases. | journal=Medicine (Baltimore) | year= 1957 | volume= 36 | issue= 4 | pages= 397-463 | pmid=13492895 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13492895  }}</ref>  
* From 1933 to 1944, Hamman and Rich described some cases of IPF. Dr. Hamman and Rich described the clinical and pathological features of a lung disease at which they named it as "acute diffuse interstitial fibrosis of the lungs". The clinical features included dyspnea, cyanosis, and cough. The histological features included alveolar edema, erythrocytosis, and hyalinization.<ref name="pmid13492895">{{cite journal| author=RUBIN EH, LUBLINER R| title=The Hamman-Rich syndrome: review of the literature and analysis of 15 cases. | journal=Medicine (Baltimore) | year= 1957 | volume= 36 | issue= 4 | pages= 397-463 | pmid=13492895 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13492895  }}</ref>  
* In 1945, based on the description of Dr. Hamman and Rich, Dr. Eder described fingers and toes clubbing as another clinical feature of IPF.  
* In 1945, based on the description of Dr. Hamman and Rich, Dr. Eder described fingers and toes clubbing as another clinical feature of IPF.<ref name="pmid14442176">{{cite journal| author=SCADDING JG| title=Chronic diffuse interstitial fibrosis of the lungs. | journal=Br Med J | year= 1960 | volume= 1 | issue= 5171 | pages= 443-50 | pmid=14442176 | doi= | pmc=1967035 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14442176  }}</ref>
* In 1949, it had been reported that the chronic form of IPF is more common than the acute diseae.   
* In 1949, it had been reported that the chronic form of IPF is more common than the acute diseae.   


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[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Medicine]]
[[Category:Up-To-Date]]
[[Category:Primary Care]

Latest revision as of 18:39, 9 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Pulmonary fibrosis was first dexcribed by Dr. Von Buhl in 1872. Dr. Rindfleish reported a case of a 40 year old patient who presented with worsening cough and dyspnea and he named this case as "Cirrhosis cystica pulmonum" in 1898.

Historical Perspective

Discovery

  • In 1872, Von Buhl reported pulmonary histologic findings which included infiltration of the lung with fibroblasts and excessive connective tissue. Dr. Von buhl reported this cases as a desquamative pneumonia due to desquamation of the alveolar and bronchiolar epithelium. Dr. Von buhl also used the term chronic interstitial pneumonia for the chronic cases and he assumed the cause to be tuberculosis or syphilis.[1]
  • In 1898, Dr. Rindfleisch reported a case of a 40 year old man who presented with worsening cough and dyspnea which are related to idiopathic pulmonary fibrosis. Dr. Rindfleisch described a a small stiffed lungs and hypertrophied right ventricles. The lungs contained dense fibrous tissues with round cells. Dr. Rindfleisch used the term "Cirrhosis cystica pulmonum" for this case at that time.
  • In 1907, Dr. Sandoz reported a case in twin sisters who presented also with worsening cough and dyspnea. Both cases had a hypertrophic right ventricle and small lungs with thickened bronchioli and dense interstitial tissue. Dr. Sandoz named this case as "Fetal bronchiectasis".
  • In 1912, Dr. von Hansemann reported five cases with lung interstitial abnormalities in the histologic examination. Dr. von Hansemann named those cases as "lymphangitis reticularis pulmonum".
  • From 1933 to 1944, Hamman and Rich described some cases of IPF. Dr. Hamman and Rich described the clinical and pathological features of a lung disease at which they named it as "acute diffuse interstitial fibrosis of the lungs". The clinical features included dyspnea, cyanosis, and cough. The histological features included alveolar edema, erythrocytosis, and hyalinization.[2]
  • In 1945, based on the description of Dr. Hamman and Rich, Dr. Eder described fingers and toes clubbing as another clinical feature of IPF.[3]
  • In 1949, it had been reported that the chronic form of IPF is more common than the acute diseae.

References

  1. Homolka J (1987). "Idiopathic pulmonary fibrosis: a historical review". CMAJ. 137 (11): 1003–5. PMC 1267422. PMID 3315158.
  2. RUBIN EH, LUBLINER R (1957). "The Hamman-Rich syndrome: review of the literature and analysis of 15 cases". Medicine (Baltimore). 36 (4): 397–463. PMID 13492895.
  3. SCADDING JG (1960). "Chronic diffuse interstitial fibrosis of the lungs". Br Med J. 1 (5171): 443–50. PMC 1967035. PMID 14442176.

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