Idiopathic pulmonary fibrosis surgery
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Idiopathic pulmonary fibrosis Microchapters |
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Differentiating Idiopathic pulmonary fibrosis from other Diseases |
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Risk calculators and risk factors for Idiopathic pulmonary fibrosis surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.
Indications
Indications of lung transplantation include:
- Patients younger than 65 years old
- Patients with low body mass index (<26 kg/m2)
Surgery
Lung transplantation
- Lung transplantation is essential in treatment of patients with idiopathic pulmonary fibrosis. Pulmonary fibrosis is the most common interstitial lung disease requiring lung transplant and it should be performed early in order to increase the survival rate.[1]
- Time of referral to lung transplantation: [2]
- Confirmed histopathologic or radiographic findings of usual interstitial pneumonitis (UIP) regardless of lung function
- Forced vital capacity (FVC) <80% predicted
- Diffusion capacity of the lung for carbon monoxide (DLCO) <40% predicted.
- Lung functional limitation (eg, dyspnea)
- Time of listing:[3]
- Decline in FVC ≥10% during 6 months of follow-up
- Decline in DLCO ≥15% during 6 months of follow-up
- Development of pulmonary hypertension
- Hospitalization due to acute exacerbation
References
- ↑ Thabut G, Mal H, Castier Y, Groussard O, Brugière O, Marrash-Chahla R; et al. (2003). "Survival benefit of lung transplantation for patients with idiopathic pulmonary fibrosis". J Thorac Cardiovasc Surg. 126 (2): 469–75. PMID 12928646.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). "A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation". J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
- ↑ Weill D, Benden C, Corris PA, Dark JH, Davis RD, Keshavjee S; et al. (2015). "A consensus document for the selection of lung transplant candidates: 2014--an update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation". J Heart Lung Transplant. 34 (1): 1–15. doi:10.1016/j.healun.2014.06.014. PMID 25085497.
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