Ventricular tachycardia laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Zand, M.D.[2]
Overview
Laboratory findings predicting sudden cardiac arrest and ventricular tachycardia include elevated level of Natriuretic peptides—B-type (BNP) or N-terminal pro-BNP as the marker of myocardial stress and fibrosis in heart failure disease, highly sensitive troponin T indicating cardiomyocyte injury, screening about hypokalemia, hypomagnesemia and also toxic level of digoxin, cocaine, tricyclic antidepressant.
Laboratory Findings
Common laboratory findings predicting sudden cardiac arrest and ventricular tachycardia include:
- Elevated level of Natriuretic peptides—B-type (BNP) or N-terminal pro-BNP as the marker of myocardial stress and fibrosis in heart failure disease predicting SCD[1]
- Highly sensitive troponin T indicating cardiomyocyte injury[2]
- Electrolytes abnormality such as hypokalemia, hypomagnesemia relation QT prolongation and torsades de pointes[3]
- Tricyclic antidepressant poisoning associated with QT prolongation [5]
- Cocaine toxicology screening[6]
| Laboratory Pearls for Ventricular Tachycardia | |
|---|---|
| Electrolytes | Hypokalemia and hypomagnesemia frequently associated with torsades de pointes |
| Troponin I | Elevated in myocardial infarction |
| Creatine-kinase MB | Elevated in myocardial infarction |
References
- ↑ Ahmad, Tariq; Fiuzat, Mona; Neely, Benjamin; Neely, Megan L.; Pencina, Michael J.; Kraus, William E.; Zannad, Faiez; Whellan, David J.; Donahue, Mark P.; Piña, Ileana L.; Adams, Kirkwood F.; Kitzman, Dalane W.; O'Connor, Christopher M.; Felker, G. Michael (2014). "Biomarkers of Myocardial Stress and Fibrosis as Predictors of Mode of Death in Patients With Chronic Heart Failure". JACC: Heart Failure. 2 (3): 260–268. doi:10.1016/j.jchf.2013.12.004. ISSN 2213-1779.
- ↑ Hussein, Ayman A.; Gottdiener, John S.; Bartz, Traci M.; Sotoodehnia, Nona; deFilippi, Christopher; Dickfeld, Timm; Deo, Rajat; Siscovick, David; Stein, Phyllis K.; Lloyd-Jones, Donald (2013). "Cardiomyocyte Injury Assessed by a Highly Sensitive Troponin Assay and Sudden Cardiac Death in the Community". Journal of the American College of Cardiology. 62 (22): 2112–2120. doi:10.1016/j.jacc.2013.07.049. ISSN 0735-1097.
- ↑ Laslett, David B.; Cooper, Joshua M.; Greenberg, Richard M.; Yesenosky, George A.; Basil, Anuj; Gangireddy, Chethan; Whitman, Isaac R. (2020). "Electrolyte Abnormalities in Patients Presenting With Ventricular Arrhythmia (from the LYTE-VT Study)". The American Journal of Cardiology. 129: 36–41. doi:10.1016/j.amjcard.2020.04.051. ISSN 0002-9149.
- ↑ Menduiña, Manuel J.; Candel, José M.; Alaminos, Pilar; Gómez, Francisco J.; Vilchez, José (2005). "Bidirectional Ventricular Tachycardia Due to Digitalis Poisoning". Revista Española de Cardiología (English Edition). 58 (8): 991–993. doi:10.1016/S1885-5857(06)60385-X. ISSN 1885-5857.
- ↑ Sabah K, Chowdhury AW, Islam MS, Saha BP, Kabir SR, Kawser S (July 2017). "Amitriptyline-induced ventricular tachycardia: a case report". BMC Res Notes. 10 (1): 286. doi:10.1186/s13104-017-2615-8. PMC 5513042. PMID 28709467. Vancouver style error: initials (help)
- ↑ Hoffman, Robert S. (2010). "Treatment of patients with cocaine-induced arrhythmias: bringing the bench to the bedside". British Journal of Clinical Pharmacology. 69 (5): 448–457. doi:10.1111/j.1365-2125.2010.03632.x. ISSN 0306-5251.