Triamcinolone detailed information

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Triamcinolone detailed information

Gene therapy
Clinical data
Pregnancy category	A (Au), C (US)
Routes of administration	Oral, topical, IM, intra-articular, intrasynovial
ATC code	A01AC01 (WHO) D07AB09 (WHO), D07XB02 (WHO), H02AB08 (WHO), R01AD11 (WHO), R03BA06 (WHO), S01BA05 (WHO)
Physiological data
Legal status
Legal status	UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Protein binding	68%
Metabolism	Hepatic
Elimination half-life	88 minutes
Excretion	Fecal and renal
Identifiers
IUPAC name 9-fluoro-11,16,17-trihydroxy-17- (2-hydroxyacetyl) -10,13-dimethyl-6,7,8,9,10,11,12, 13,14,15,16,17- dodecahydrocyclopenta[a]phenanthren-3-one
CAS Number	124-94-7
PubChem Template:Abbreviation	31307
DrugBank	APRD00422
Chemical and physical data
Formula	C21H27FO6
Molar mass	394.434 g/mol

Triamcinolone (trade names Kenalog, Aristocort, Nasacort, Tri-Nasal, Triderm, Azmacort, Trilone, Volon A, Tristoject, Fougera;) is a synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream.

Uses

They are also used in the post-operative period of certain cosmetic surgery procedures, notably rhinoplasty. Injected into the subcutaneous area, they may help to alleviate stubborn swelling and decrease the presence of scar tissue.

Topical triamcinolone acetonide paste is often prescribed for mouth or gum irritation following dental procedures.

Triamcinolone is occasionally used to treat severe cases of hayfever.

Forms

Different triamcinolone salts are available, including acetonide, hexacetonide and diacetate.

Triamcinolone acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone.

External links

• Template:MedlinePlusDrugInfo
• Cautions for Triamcinolone Use
• Significant drug interactions with triamcinolone

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