Squamous cell carcinoma of the lung history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

The hallmark of squamous cell carcinoma of the lung is chronic cough, weight loss, and hemoptysis. A positive history of smoking may be suggestive of squamous cell carcinoma of the lung. Symptoms related with squamous cell carcinoma of the lung will vary depending on the size and location of the tumor. Common symptoms of squamous cell carcinoma of the lung may also include shortness of breath, fatigue, and chest pain. Less common symptoms of squamous cell carcinoma of the lung include bone pain, fatigue, dizziness, dysphagia, and numbness in extremities.

History and Symptoms

History

  • Obtaining the history is an important aspect of making a diagnosis of squamous cell carcinoma of the lung.
  • It provides insight into natural evolution of the disease.
  • Complete history will help determine the likelihood of metastases, and the association with other conditions.
  • Specific symptoms description such as duration, onset, and progression are important for making the diagnosis.
  • Specific areas of focus when obtaining the history are outlined below:[1]
    • Family history of cancer
    • Personal history of cancer
  • Positive history of active/passive smoking
  • Number of cigarettes/year
  • Number of years/months of active smoking
  • Number of years/months of smoking cessation
  • Associated conditions, such as:

Common Symptoms

Less Common Symptoms

  • Other less common symptoms of non-small cell lung cancer include:[5]

Late Symptoms

References

  1. Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
  2. Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter |coauthors= ignored (help)
  3. Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015
  4. Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM (2007). "Natural history of stage I non-small cell lung cancer: implications for early detection". Chest. 132 (1): 193–9. doi:10.1378/chest.06-3096. PMID 17505036.
  5. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2018/cancer-facts-and-figures-2018.pdf