Nasopharyngeal carcinoma classification
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Differentiating Nasopharyngeal carcinoma from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]Faizan Sheraz, M.D. [3]
Overview
World health organization classified nasopharyngeal carcinoma into 3 types : keratinizing, nonkeratinizing (differentiated, undifferentiated) and basaloid squamous cell carcinoma.
Classification
World Health Organization (WHO) classification (2005) for nasopharyngeal carcinoma (NPC):[1][2]
| Classification | Former name | EBV | Prevalence | Prognosis |
|---|---|---|---|---|
| Keratinizing | Type 1, squamous cell carcinoma | -ve | almost 1/4 of NPC cases | poor |
| Nonkeratinizing, differentiated | Type 2, transitional carcinoma | +ve | less than 1/6 of NPC cases | good |
| Nonkeratinizing, undifferentiated | Type 3, lymphoepithelial carcinoma | +ve | most common | good |
| Basaloid squamous cell carcinoma (BSCC) | least common | poor |
References
- ↑ Barnes, Leon (2005). Pathology and genetics of head and neck tumours. Lyon: IARC Press. ISBN 978-92-832-2417-4.
- ↑ Thompson, Lester (2011). Diagnostic pathology. Salt Lake City, Utah: Amirsys. ISBN 1931884617.