Myasthenia gravis electrocardiogram

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

There is controversy about ECG changes in MG. These changes are mostly non specific but the fact that they will regress after treatment of MG will rise this suspicion that MG causes these abnormalities. These abnormalities include  arrhythmias (which can increase the risk of sudden cardiac death, Q-T prolongation, conduction disturbances and ST-T changes.

Electrocardiogram

  • There is controversy about ECG changes in MG.[1] These changes are mostly non specific but the fact that they will regress after treatment of MG will rise this suspicion that MG causes these abnormalities.[2][3]
  • These abnormalities include  arrhythmias (which can increase the risk of sudden cardiac death[4], Q-T prolongation[3], conduction disturbances and ST-T changes.[2][3][5]

References

  1. Gibson TC (September 1975). "The heart in myasthenia gravis". Am. Heart J. 90 (3): 389–96. PMID 1099888.
  2. 2.0 2.1 KOHN PM, TUCKER HJ, KOZOKOFF NJ (May 1965). "THE CARDIAC MANIFESTATIONS OF MYASTHENIA GRAVIS WITH PARTICULAR REFERENCE TO ELECTROCARDIOGRAPHIC ABNORMALITIES". Am. J. Med. Sci. 249: 561–70. PMID 14280896.
  3. 3.0 3.1 3.2 Büyüköztürk K, Ozdemir C, Kohen D (1976). "Electrocardiographic findings in 24 patients with myasthenia gravis". Acta Cardiol. 31 (4): 301–5. PMID 139069.
  4. Hofstad H, Ohm OJ, Mørk SJ, Aarli JA (September 1984). "Heart disease in myasthenia gravis". Acta Neurol. Scand. 70 (3): 176–84. PMID 6507031.
  5. Luomanmäki K, Hokkanen E, Heikkilä J. "Electrocardiogram in myasthenia gravis. Analysis of a series of 97 patients". Ann. Clin. Res. 1 (4): 236–45. PMID 5371909. Unknown parameter |adate= ignored (help)


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