Medullary thyroid cancer laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Laboratory findings consistent with the diagnosis of medullary thyroid cancer include decreased thyroid stimulating hormone, elevated calcitonin, and decreased calcium.
Laboratory Findings
- Blood or imaging tests may be done prior to or in lieu of a biopsy. The following blood tests are conducted:
- Thyroid stimulating hormone (TSH)
- Thyroxine (T4)
- Triiodothyronine (T3)
- Calcitonin- Calcitonin is required for the diagnosis and follow up of medullary thyroid cancer. It is an important tumor marker.
- Carcinoembryonic antigen
- Tests for serum thyroid autoantibodies are done to rule out autoimmune thyroid disease.
- Laboratory findings consistent with the diagnosis of multiple endocrine neoplasia type 2 are tabulated below.
| Test | Findings |
|---|---|
| Metabolic | Decreased thyroid stimulating hormone Antithyroid antibodies Elevated calcitonin Decreased calcium |
| Adapted from Arzu Tatlıpınar1 and İlkay Kartal [Updated 2015].The Evaluation of Thyroid Nodules. Journal of Thyroid Disorders & Therapy.2015.[1] | |
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