Lymphoplasmacytic lymphoma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Overview

There are no specific MRI findings associated with lymphoplasmacytic lymphoma. However, MRI of the brain, spinal cord and orbits is especially important while assessing hyperviscosity and for diagnosing Bing-Neel syndrome.

MRI

• There are no specific MRI findings associated with lymphoplasmacytic lymphoma.
• However, MRI of the brain, spinal cord and orbits is important when assessing for hyperviscosity in the presence of high IgM paraprotein in the blood especially important when diagnosing Bing-Neel syndrome.

MRI brain coronal view shows diffuse meningeal enhancement in a patient with Bing-Neel syndrome. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC4837273_CRIHEM2016-3931709.002&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=69 Source: Halperin D. et al, Whipps Cross Hospital, London E11 1NR, UK. ]

Coronal T1-weighted (TR 600, TE 30) 3mm noncontrast sections through the inner ear in a patient with Waldenstrom macroglobulinemia with bilateral hearing loss. Arrows indicate hemorrhage within the labyrinth. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC4891550_gr2&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=67 Source: Shibata DK. et al. ]

Axial T1-weighted (TR 700, TE 30) 3mm noncontrast sections through the petrous bone in a patient with Waldenstrom macroglobulinemia with bilateral hearing loss. Arrows indicate T1 shortening within the labyrinth. [https://openi.nlm.nih.gov/detailedresult.php?img=PMC4891550_gr1&query=waldenstrom+macroglobulinaemia&it=xg&req=4&npos=66 Source: Shibata DK. et al. ]