Goodpasture syndrome physical examination

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Goodpasture syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Krzysztof Wierzbicki M.D. [3] Akshun Kalia M.B.B.S.[4]

Overview

A complete medical history and comprehensive renal and pulmonary exam must be performed to help identify and properly diagnose Goodpasture syndrome.The presence of tachypnea, inspiratory crackles, edema and hypertension on physical examination are suggestive of presence of renal and pulmonary disorders such as Goodpasture syndrome.

Physical Examination

A complete medical history and comprehensive renal and pulmonary exam must be performed to help identify and properly diagnose Goodpasture syndrome. A thorough physical examination can provide insight into possible causes and associated underlying conditions. The following findings may be present during a physical examination of Goodpasture syndrome:[1]

Appearance of the Patient

  • Patients with Goodpasture syndrome usually appear fatigued.

Vital Signs

Skin

  • Skin examination of patients with severe Goodpasture syndrome may present with cyanosis from autoantibodies induced lung injury.

HEENT

  • HEENT examination of patients with Goodpasture syndrome is usually normal.

Lungs

  • Lungs are hyporresonant
  • Fine Crackles upon auscultation of the lung bases may be present unilaterally/bilaterally

Abdomen

Genitourinary

Extremities

Extremities examination of patients with Goodpasture syndrome may present with:

References

  1. Greco A, Rizzo MI, De Virgilio A, Gallo A, Fusconi M, Pagliuca G; et al. (2015). "Goodpasture's syndrome: a clinical update". Autoimmun Rev. 14 (3): 246–53. doi:10.1016/j.autrev.2014.11.006. PMID 25462583.

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