Diffuse large B cell lymphoma biopsy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2] Anila Hussain, MD [3]

Overview

Excisional Lymph node or extranodal tissue biopsy is diagnostic of diffuse large B cell lymphoma.

Biopsy

  • Surgical Excision Biopsy of Lymph node or extranodal tissue is diagnostic of diffuse large B cell lymphoma.[1]
  • Needle-Core Excision and Endoscopic Biopsies should be reserved for patients in which surgery is too risky or impractical.
  • FNA not used for diagnosis alone.
  • To view findings on biopsy characteristic of each morphological variant of diffuse large B cell lymphoma, click here.
  • morphological Diagnosis of DLBCL on Biopsy should always be confirmed by Immunophenotypic techniques like Flow cytometry or IHC or Both.

References

  1. National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov


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