Crohn's disease risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Common risk factors in the development of crohns disease include white ancestry, age 15-40 or 60-80 years, family history of crohns disease and cigarette smoking.

Risk Factors

Common risk factors in the development of crohns disease include [1][2][3]

  • White ancestry
  • Age 15-40 or 60-80 years
  • Family history of CD
  • Cigarette smoking, smokers are three times more likely to get Crohn's disease.
  • Diet rich in sugars
  • Oral contraceptives
  • NSAIDS
  • Living in an industrialized country
  • Certain chemicals in the diet, known as microparticles, are also hypothesized as a risk factor for the disease, as well as a poor imbalance of omega-6 to healthy omega-3 fatty acids that emerging research shows helps to improve all types of inflammatory disease.
  • Gastric cancer is most often caused by the bacterium Helicobacter pylori that flourishes in cramped and unsanitary conditions.

References

  1. Cosnes J (2004). "Tobacco and IBD: relevance in the understanding of disease mechanisms and clinical practice". Best Pract Res Clin Gastroenterol. 18 (3): 481–96. PMID 15157822.
  2. Morris, Danielle L (2000-11-18). "Early environmental factors may have role in both Crohn's disease and gastric carcinoma - Letter to the Editor". British Medical Journal. Retrieved 2008-01-16.
  3. Lesko S, Kaufman D, Rosenberg L; et al. (1985). "Evidence for an increased risk of Crohn's disease in oral contraceptive users". Gastroenterology. 89 (5): 1046–9. PMID 4043662.

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