Crohn's disease classification
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Crohn's disease |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Crohn's disease can affect any part of the gastrointestinal tract expect rectum. Crohn's disease may be classified based on the area of involvement and based on the behavior of the disease progression.
Classification
Crohn's disease can affect any part of the gastrointestinal tract expect rectum. It can be classified based on the area of involvement and based on the behavior of the disease progression. Individuals affected by the Crohn's disease rarely fall outside these classifications.
Based on the area of involvement
- Ileocolic Crohn's disease
- Crohn's disease involving both the ileum and the large intestine, accounts for 50% of cases.
- Crohn's ileitis
- Crohn's disease involving ileum only, accounts for 30% of cases.
- Crohn's colitis
- Crohn's disease involving prendominantly only large intestine. Often difficult to distinguish from ulcerative colitis.
Based on the behavior of disease
Crohn's disease may also be classified by the behavior of disease as it progresses. This was formalized in the Vienna classification of Crohn's disease.[1] There are three categories of disease presentation in Crohn's disease:
- Stricturing disease
- Causes narrowing of the bowel which may lead to bowel obstruction or changes in the caliber of the feces.
- Penetrating disease
- Creates abnormal passageways (fistulae) between the bowel and other structures such as the skin.
- Inflammatory disease (or non-stricturing, non-penetrating disease)
- Causes inflammation without causing strictures or fistulae.[1][2]
References
- ↑ 1.0 1.1 Gasche C, Scholmerich J, Brynskov J, D'Haens G, Hanauer S, Irvine E, Jewell D, Rachmilewitz D, Sachar D, Sandborn W, Sutherland L (2000). "A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998". Inflamm Bowel Dis. 6 (1): 8–15. PMID 10701144.
- ↑ Dubinsky MC, Fleshner PP. (2003). "Treatment of Crohn's Disease of Inflammatory, Stenotic, and Fistulizing Phenotypes". Curr Treat Options Gastroenterol. 6 (3): 183–200. PMID 12744819.