Complement component 9
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complement component 9 | |
---|---|
Identifiers | |
Symbol | C9 |
Entrez | 735 |
HUGO | 1358 |
OMIM | 120940 |
RefSeq | NM_001737 |
UniProt | P02748 |
Other data | |
Locus | Chr. 5 p13 |
Complement component 9 (C9) is a protein involved in the complement system, which is part of the innate immune system.[1] C9 is a member of the complement membrane attack complex (MAC) and induces pores on cell membranes, causing lysis. There are 10-16 molecules of C9 in a single membrane attack complex (MAC), along with one of each of the complement components C5b, C6, C7 and C8.[2]
References
- ↑ Lint TF, Zeitz HJ, Gewurz H (November 1980). "Inherited deficiency of the ninth component of complement in man". J. Immunol. 125 (5): 2252–7. PMID 7430628.
- ↑ Janeway, CA Jr; Travers P; Walport M; et al. (2001). "The complement system and innate immunity". Immunobiology: The Immune System in Health and Disease. New York: Garland Science. Retrieved 29 December 2017.
External links
- Complement+9 at the US National Library of Medicine Medical Subject Headings (MeSH)
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