Alkylglycerone phosphate synthase
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|PDB structures||RCSB PDB PDBe PDBsum|
|Gene Ontology||AmiGO / QuickGO|
|alkylglycerone phosphate synthase|
|Locus||Chr. 2 q31|
Alkylglycerone phosphate synthase (EC 18.104.22.168, alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetone phosphate synthetase, alkyl DHAP synthetase, alkyl-DHAP, dihydroxyacetone-phosphate acyltransferase, DHAP-AT) is an enzyme associated with Type 3 Rhizomelic chondrodysplasia punctata. This enzyme catalyses the following chemical reaction
- 1-acyl-glycerone 3-phosphate + a long-chain alcohol <math>\rightleftharpoons</math> an alkyl-glycerone 3-phosphate + a long-chain acid anion
- ↑ Brown AJ, Snyder F (August 1982). "Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism". The Journal of Biological Chemistry. 257 (15): 8835–9. PMID 7096336.
- ↑ Wykle RL, Plantadosi C, Snyder F (May 1972). "The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor". The Journal of Biological Chemistry. 247 (9): 2944–8. PMID 4401994.
- Alkylglycerone-phosphate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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