Stomach cancer differential diagnosis: Difference between revisions

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{{CMG}}
__NOTOC__
{{Stomach cancer}}
{{Stomach cancer}}
{{CMG}}{{AE}}{{PSD}}
==Overview==
[[Stomach cancer]] must be differentiated from other [[diseases]] presenting with episodic [[abdominal pain]], [[weight loss]] and [[loss of appetite]] such as [[gastric lymphoma]], [[gastric]] [[metastasis]], [[gastritis]], [[Peptic ulcer|benign gastric ulcer]], [[Ménétrier's disease|Menetrier's disease]].
==Differential Diagnosis==
[[Stomach cancer]] must be differentiated from other [[diseases]] presenting with episodic [[abdominal pain]], [[weight loss]] and [[loss of appetite]]. The differentials include the following:<ref name="pmid6710074">{{cite journal| author=Sugimachi K, Inokuchi K, Kuwano H, Ooiwa T| title=Acute gastritis clinically classified in accordance with data from both upper GI series and endoscopy. | journal=Scand J Gastroenterol | year= 1984 | volume= 19 | issue= 1 | pages= 31-7 | pmid=6710074 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6710074  }} </ref><ref name="pmid25901896">{{cite journal| author=Sipponen P, Maaroos HI| title=Chronic gastritis. | journal=Scand J Gastroenterol | year= 2015 | volume= 50 | issue= 6 | pages= 657-67 | pmid=25901896 | doi=10.3109/00365521.2015.1019918 | pmc=4673514 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25901896  }} </ref><ref name="pmid16819502">{{cite journal| author=Sartor RB| title=Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. | journal=Nat Clin Pract Gastroenterol Hepatol | year= 2006 | volume= 3 | issue= 7 | pages= 390-407 | pmid=16819502 | doi=10.1038/ncpgasthep0528 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16819502  }} </ref><ref name="pmid2789799">{{cite journal| author=Sipponen P| title=Atrophic gastritis as a premalignant condition. | journal=Ann Med | year= 1989 | volume= 21 | issue= 4 | pages= 287-90 | pmid=2789799 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2789799  }} </ref><ref name="pmid25133039">{{cite journal| author=Badillo R, Francis D| title=Diagnosis and treatment of gastroesophageal reflux disease. | journal=World J Gastrointest Pharmacol Ther | year= 2014 | volume= 5 | issue= 3 | pages= 105-12 | pmid=25133039 | doi=10.4292/wjgpt.v5.i3.105 | pmc=4133436 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25133039  }} </ref><ref name="pmid17956071">{{cite journal| author=Ramakrishnan K, Salinas RC| title=Peptic ulcer disease. | journal=Am Fam Physician | year= 2007 | volume= 76 | issue= 7 | pages= 1005-12 | pmid=17956071 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17956071  }} </ref><ref name="pmid17985090">{{cite journal| author=Banasch M, Schmitz F| title=Diagnosis and treatment of gastrinoma in the era of proton pump inhibitors. | journal=Wien Klin Wochenschr | year= 2007 | volume= 119 | issue= 19-20 | pages= 573-8 | pmid=17985090 | doi=10.1007/s00508-007-0884-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17985090  }} </ref><ref name="pmid15621988">{{cite journal| author=Dicken BJ, Bigam DL, Cass C, Mackey JR, Joy AA, Hamilton SM| title=Gastric adenocarcinoma: review and considerations for future directions. | journal=Ann Surg | year= 2005 | volume= 241 | issue= 1 | pages= 27-39 | pmid=15621988 | doi= | pmc=1356843 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15621988  }} </ref><ref name="pmid21390139">{{cite journal| author=Ghimire P, Wu GY, Zhu L| title=Primary gastrointestinal lymphoma. | journal=World J Gastroenterol | year= 2011 | volume= 17 | issue= 6 | pages= 697-707 | pmid=21390139 | doi=10.3748/wjg.v17.i6.697 | pmc=3042647 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21390139  }} </ref>
<div style="width: 85%;">
<small>
{| style="border: 0px; font-size: 90%; margin: 3px;" align="center"
| colspan="13" style="background: #4479BA; text-align: center;" | {{fontcolor|#FFF|'''Differential Diagnosis'''}}
|+
| rowspan="3" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Disease'''}}
| rowspan="3" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Cause'''}}
| colspan="9" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Symptoms'''}}
| style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Diagnosis'''}}
| rowspan="3" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Other findings'''}}
|-
| colspan="3" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Pain'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Nausea & Vomiting'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Heartburn'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Belching or Bloating'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Weight loss'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Loss of Appetite'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Stools'''}}
| rowspan="2" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Endoscopy findings'''}}
|-
| rowspan="1" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Location'''}}
| rowspan="1" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Aggravating Factors'''}}
| rowspan="1" style="background:#4479BA; padding: 5px 5px;" align="center" |{{fontcolor|#FFF|'''Alleviating Factors'''}}
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Acute gastritis]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* ''[[H. pylori]]''
* [[NSAIDS]]
* [[Corticosteroids]]
* [[Alcohol]]
* Spicy [[food]]
* [[Viral infections]]
* [[Crohn's disease]]
* [[Autoimmune diseases]]
* [[Bile]] reflux
* [[Cocaine]] use
* Breathing machine or [[ventilator]]
* Ingestion of [[corrosive|corrosives]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Epigastric pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | [[Food]]
| style="padding: 5px 5px; background: #F5F5F5;" | [[Antacids]]
| style="padding: 5px 5px; background: #F5F5F5;" |  ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | [[Melena|Black stools]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Pangastritis]] or antral [[gastritis]]
* [[Gastric erosion|Erosive]] (Superficial, deep, [[hemorrhagic]])
* Nonerosive (''[[H. pylori]]'')
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Gastritis|Chronic gastritis]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* ''[[H. pylori]]''
* [[Alcohol]]
* Medications
* [[Autoimmune diseases]]
* Chronic [[stress]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Epigastric pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | [[Food]]
| style="padding: 5px 5px; background: #F5F5F5;" | [[Antacids]]
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ''[[H. pylori]] [[gastritis]]''
* [[Atrophy]]
* [[Intestinal]] [[metaplasia]]
Lymphocytic [[gastritis]]
* Enlarged folds
* Aphthoid erosions
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Atrophic gastritis]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* ''[[H. pylori]]''
* [[Autoimmune disease]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*[[Epigastric pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ''[[H. pylori]]''
* [[Mucosal]] [[atrophy]]
[[Autoimmune]]
* [[Mucosal]] [[atrophy]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Iron deficiency anemia]]
*Autoimmune gastritis diagnosis includes:
**Antiparietal and anti-IF antibodies
**[[Achlorhydria]] and hypergastrinemia
**Low serum [[vitamin B12|cobalamine]]
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Crohn's disease]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Autoimmune disease]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Abdominal pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" |
* Chronic [[diarrhea]] often bloody with [[pus]] or [[mucus]]
* [[Rectal bleeding]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Mucosal]] nodularity with cobblestoning
* Multiple [[aphthous ulcers]]
* Linier or serpiginous [[ulcerations]]
* Thickened antral folds
* Antral narrowing
* Hypoperistalsis
* [[Duodenal]] strictures
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Fever]]
* [[Fatigue]]
* [[Anemia]] ([[pernicious anemia]])
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[GERD]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Lower esophageal sphincter]] abnormalities
* [[Hiatal hernia]]
* Abnormal [[esophageal]] contractions
* Prolonged emptying of [[stomach]]
* [[Gastrinomas|Gastrinoma]]<nowiki/>s
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Epigastric pain]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* Spicy food
* Tight fitting clothing
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Antacids]]
* Head elevation during sleep
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
(Suspect delayed gastric emptying)
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Esophagitis]]
* [[Barrette's esophagus]]
* [[Strictures]]
| style="padding: 5px 5px; background: #F5F5F5;" | Other symptoms:
* [[Dysphagia]]
* [[Regurgitation]]
* [[Cough|Nocturnal cough]]
* [[Hoarseness]]
Complications
* [[Esophagitis]]
* [[Strictures]]
* Barrette esophagus
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Peptic ulcer disease]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* ''[[H. pylori]]''
* [[Smoking]]
* [[Alcohol]]
* [[Radiation therapy]]
* Medications
* Zollinger-ellison syndrome
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Epigastric pain]] sometimes extending to back
* [[Right upper quadrant pain]]
| style="padding: 5px 5px; background: #F5F5F5;" |
'''[[Duodenal ulcer]]'''
*Pain aggravates with empty stomach
'''[[Gastric ulcer]]'''
*Pain aggravates with food
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Antacids]]
* [[Duodenal ulcer]]
:*Pain alleviates with food
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Melena|Black stools]]
| style="padding: 5px 5px; background: #F5F5F5;" | '''Gastric ulcers'''
* Discrete [[mucosal]] [[lesions]] with a punched-out smooth [[ulcer]] base with whitish fibrinoid base
* Most [[ulcers]] are at the junction of [[fundus]] and [[antrum]]
* 0.5-2.5cm
'''Duodenal ulcers'''
* Well-demarcated break in the [[mucosa]] that may extend into the [[muscularis propria]] of the [[duodenum]]
* Found in the first part of [[duodenum]]
* <1cm
| style="padding: 5px 5px; background: #F5F5F5;" | '''Other diagnostic tests'''
* Serum [[gastrin]] levels
* [[Secretin]] stimulation test
* [[Biopsy]]
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Gastrinoma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* Associated with [[MEN type 1]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Abdominal pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
(suspect [[gastric outlet obstruction]])
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Melena|Black stools]]
| style="padding: 5px 5px; background: #F5F5F5;" | Useful in collecting the tissue for [[biopsy]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* May present with symptoms of [[GERD]] or [[peptic ulcer disease]]
* Associated with [[MEN type 1]]
'''Diagnostic tests'''
* Serum [[gastrin]] levels
* [[Somatostatin]] receptor [[scintigraphy]]
* [[CT]] and [[MRI]]
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Gastric Cancer|Gastric Adenocarcinoma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* ''[[H. pylori]]'' infection
* Smoked and salted food
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Abdominal pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Melena|Black stools]], or blood in stools
| style="padding: 5px 5px; background: #F5F5F5;" | '''Esophagogastroduodenoscopy'''
* Multiple biopsies are taken to establish the diagnosis
| style="padding: 5px 5px; background: #F5F5F5;" | '''Other symptoms'''
* [[Dysphagia]]
* Early [[satiety]]
* Frequent [[burping]]
|-
| style="padding: 5px 5px; background: #DCDCDC;" |[[Gastric lymphoma|Primary gastric lymphoma]]
| style="padding: 5px 5px; background: #F5F5F5;" |
* ''[[H. pylori]]'' infection
| style="padding: 5px 5px; background: #F5F5F5;" |
* [[Abdominal pain]]
* [[Chest pain]]
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | ✔
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | <nowiki>-</nowiki>
| style="padding: 5px 5px; background: #F5F5F5;" | Useful in collecting the [[tissue]] for [[biopsy]]
| style="padding: 5px 5px; background: #F5F5F5;" | '''Other symptoms'''
* Painless swollen [[lymph nodes]] in neck and armpit
* Night sweats
* [[Fatigue]]
* [[Fever]]
* [[Cough]] or trouble breathing
|}
</small>
</div>


==Overview==
'''Stomach cancer''' (also called '''gastric cancer''') can develop in any part of the [[stomach]] and may spread throughout the stomach and to other organs; particularly the [[esophagus]] and the [[small intestine]]. Stomach cancer causes nearly one million deaths worldwide per year.<ref name="WHO">{{cite web | last = | first = | authorlink = | coauthors = | title =Cancer | work = | publisher =World Health Organization | date =Feb 2006 | url =http://www.who.int/mediacentre/factsheets/fs297/en/ | format = | doi = | accessdate =2007-05-24 }}</ref>
==References==
==References==
{{Reflist|2}}
{{reflist|2}}


{{WH}}
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[[Category: Oncology]]
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Conditions diagnosed by stool test]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gastroenterology]]
[[Category:Surgery]]

Latest revision as of 00:18, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]

Overview

Stomach cancer must be differentiated from other diseases presenting with episodic abdominal pain, weight loss and loss of appetite such as gastric lymphoma, gastric metastasis, gastritis, benign gastric ulcer, Menetrier's disease.

Differential Diagnosis

Stomach cancer must be differentiated from other diseases presenting with episodic abdominal pain, weight loss and loss of appetite. The differentials include the following:[1][2][3][4][5][6][7][8][9]

Differential Diagnosis
Disease Cause Symptoms Diagnosis Other findings
Pain Nausea & Vomiting Heartburn Belching or Bloating Weight loss Loss of Appetite Stools Endoscopy findings
Location Aggravating Factors Alleviating Factors
Acute gastritis Food Antacids ✔ ✔ ✔ - ✔ Black stools -
Chronic gastritis Food Antacids ✔ ✔ ✔ ✔ ✔ - H. pylori gastritis

Lymphocytic gastritis

  • Enlarged folds
  • Aphthoid erosions
 -
Atrophic gastritis - - ✔ - ✔ ✔ - H. pylori

Autoimmune

Crohn's disease - - - - - ✔ ✔
GERD
  • Spicy food
  • Tight fitting clothing
 ✔

(Suspect delayed gastric emptying)

✔ - - - - Other symptoms:

Complications

Peptic ulcer disease

Duodenal ulcer

  • Pain aggravates with empty stomach

Gastric ulcer

  • Pain aggravates with food
  • Pain alleviates with food
 ✔ ✔ - - - Gastric ulcers

Duodenal ulcers

Other diagnostic tests
Gastrinoma - - ✔

(suspect gastric outlet obstruction)

✔ - - - Useful in collecting the tissue for biopsy

Diagnostic tests

Gastric Adenocarcinoma - - ✔ ✔ ✔ ✔ ✔ Esophagogastroduodenoscopy
  • Multiple biopsies are taken to establish the diagnosis
 Other symptoms
Primary gastric lymphoma - - - - - ✔ - - Useful in collecting the tissue for biopsy Other symptoms

References

  1. ↑ Sugimachi K, Inokuchi K, Kuwano H, Ooiwa T (1984). "Acute gastritis clinically classified in accordance with data from both upper GI series and endoscopy". Scand J Gastroenterol. 19 (1): 31–7. PMID 6710074.
  2. ↑ Sipponen P, Maaroos HI (2015). "Chronic gastritis". Scand J Gastroenterol. 50 (6): 657–67. doi:10.3109/00365521.2015.1019918. PMC 4673514. PMID 25901896.
  3. ↑ Sartor RB (2006). "Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis". Nat Clin Pract Gastroenterol Hepatol. 3 (7): 390–407. doi:10.1038/ncpgasthep0528. PMID 16819502.
  4. ↑ Sipponen P (1989). "Atrophic gastritis as a premalignant condition". Ann Med. 21 (4): 287–90. PMID 2789799.
  5. ↑ Badillo R, Francis D (2014). "Diagnosis and treatment of gastroesophageal reflux disease". World J Gastrointest Pharmacol Ther. 5 (3): 105–12. doi:10.4292/wjgpt.v5.i3.105. PMC 4133436. PMID 25133039.
  6. ↑ Ramakrishnan K, Salinas RC (2007). "Peptic ulcer disease". Am Fam Physician. 76 (7): 1005–12. PMID 17956071.
  7. ↑ Banasch M, Schmitz F (2007). "Diagnosis and treatment of gastrinoma in the era of proton pump inhibitors". Wien Klin Wochenschr. 119 (19–20): 573–8. doi:10.1007/s00508-007-0884-2. PMID 17985090.
  8. ↑ Dicken BJ, Bigam DL, Cass C, Mackey JR, Joy AA, Hamilton SM (2005). "Gastric adenocarcinoma: review and considerations for future directions". Ann Surg. 241 (1): 27–39. PMC 1356843. PMID 15621988.
  9. ↑ Ghimire P, Wu GY, Zhu L (2011). "Primary gastrointestinal lymphoma". World J Gastroenterol. 17 (6): 697–707. doi:10.3748/wjg.v17.i6.697. PMC 3042647. PMID 21390139.

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