Fyn-related kinase: Difference between revisions
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*{{cite journal |vauthors=Cance WG, Craven RJ, Bergman M |title=Rak, a novel nuclear tyrosine kinase expressed in epithelial cells. |journal=Cell Growth Differ. |volume=5 |issue= 12 |pages= 1347–55 |year= 1995 |pmid= 7696183 |doi= |display-authors=etal}} | *{{cite journal |vauthors=Cance WG, Craven RJ, Bergman M |title=Rak, a novel nuclear tyrosine kinase expressed in epithelial cells. |journal=Cell Growth Differ. |volume=5 |issue= 12 |pages= 1347–55 |year= 1995 |pmid= 7696183 |doi= |display-authors=etal}} | ||
*{{cite journal |vauthors=Cance WG, Craven RJ, Weiner TM, Liu ET |title=Novel protein kinases expressed in human breast cancer. |journal=Int. J. Cancer |volume=54 |issue= 4 |pages= 571–7 |year= 1993 |pmid= 8099900 |doi=10.1002/ijc.2910540409 }} | *{{cite journal |vauthors=Cance WG, Craven RJ, Weiner TM, Liu ET |title=Novel protein kinases expressed in human breast cancer. |journal=Int. J. Cancer |volume=54 |issue= 4 |pages= 571–7 |year= 1993 |pmid= 8099900 |doi=10.1002/ijc.2910540409 }} | ||
*{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|display-authors=etal}} | *{{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 |pmc=139241|display-authors=etal|bibcode=2002PNAS...9916899M }} | ||
*{{cite journal |vauthors=Meyer T, Xu L, Chang J |title=Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase. |journal=Int. J. Cancer |volume=104 |issue= 2 |pages= 139–46 |year= 2003 |pmid= 12569567 |doi= 10.1002/ijc.10925 |display-authors=etal}} | *{{cite journal |vauthors=Meyer T, Xu L, Chang J |title=Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase. |journal=Int. J. Cancer |volume=104 |issue= 2 |pages= 139–46 |year= 2003 |pmid= 12569567 |doi= 10.1002/ijc.10925 |display-authors=etal}} | ||
*{{cite journal |vauthors=Watanabe T, Ohnuma T, Shibata N |title=No genetic association between Fyn kinase gene polymorphisms (-93A/G, IVS10+37T/C and Ex12+894T/G) and Japanese sporadic Alzheimer's disease. |journal=Neurosci. Lett. |volume=360 |issue= 1-2 |pages= 109–11 |year= 2004 |pmid= 15082191 |doi= 10.1016/j.neulet.2004.02.046 |display-authors=etal}} | *{{cite journal |vauthors=Watanabe T, Ohnuma T, Shibata N |title=No genetic association between Fyn kinase gene polymorphisms (-93A/G, IVS10+37T/C and Ex12+894T/G) and Japanese sporadic Alzheimer's disease. |journal=Neurosci. Lett. |volume=360 |issue= 1-2 |pages= 109–11 |year= 2004 |pmid= 15082191 |doi= 10.1016/j.neulet.2004.02.046 |display-authors=etal}} | ||
*{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928|display-authors=etal}} | *{{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 |pmc=528928|display-authors=etal}} | ||
*{{cite journal |vauthors=Zhang Y, Wolf-Yadlin A, Ross PL |title=Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. |journal=Mol. Cell. Proteomics |volume=4 |issue= 9 |pages= 1240–50 |year= 2005 |pmid= 15951569 |doi= 10.1074/mcp.M500089-MCP200 |display-authors=etal}} | *{{cite journal |vauthors=Zhang Y, Wolf-Yadlin A, Ross PL |title=Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. |journal=Mol. Cell. Proteomics |volume=4 |issue= 9 |pages= 1240–50 |year= 2005 |pmid= 15951569 |doi= 10.1074/mcp.M500089-MCP200 |display-authors=etal}} | ||
*{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}} | *{{cite journal |vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal|bibcode=2005Natur.437.1173R }} | ||
}} | }} | ||
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Fyn-related kinase (FRK, formerly tyrosine protein kinase 5) is an enzyme that in humans is encoded by the FRK gene.[1][2]
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.[2]
Interactions
FRK has been shown to interact with retinoblastoma protein.[3]
References
- ↑ Lee J, Wang Z, Luoh SM, Wood WI, Scadden DT (April 1994). "Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene". Gene. 138 (1–2): 247–51. doi:10.1016/0378-1119(94)90817-6. PMID 7510261.
- ↑ 2.0 2.1 "Entrez Gene: FRK fyn-related kinase".
- ↑ Craven, R J; Cance W G; Liu E T (September 1995). "The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb". Cancer Res. UNITED STATES. 55 (18): 3969–72. ISSN 0008-5472. PMID 7664264.
Further reading
- Serfas MS, Tyner AL (2003). "Brk, Srm, Frk, and Src42A form a distinct family of intracellular Src-like tyrosine kinases". Oncol. Res. 13 (6–10): 409–19. PMID 12725532.
- Craven RJ, Cance WG, Liu ET (1995). "The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb". Cancer Res. 55 (18): 3969–72. PMID 7664264.
- Cance WG, Craven RJ, Bergman M, et al. (1995). "Rak, a novel nuclear tyrosine kinase expressed in epithelial cells". Cell Growth Differ. 5 (12): 1347–55. PMID 7696183.
- Cance WG, Craven RJ, Weiner TM, Liu ET (1993). "Novel protein kinases expressed in human breast cancer". Int. J. Cancer. 54 (4): 571–7. doi:10.1002/ijc.2910540409. PMID 8099900.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Meyer T, Xu L, Chang J, et al. (2003). "Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase". Int. J. Cancer. 104 (2): 139–46. doi:10.1002/ijc.10925. PMID 12569567.
- Watanabe T, Ohnuma T, Shibata N, et al. (2004). "No genetic association between Fyn kinase gene polymorphisms (-93A/G, IVS10+37T/C and Ex12+894T/G) and Japanese sporadic Alzheimer's disease". Neurosci. Lett. 360 (1–2): 109–11. doi:10.1016/j.neulet.2004.02.046. PMID 15082191.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
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