Aortic stenosis epidemiology and demographics: Difference between revisions
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{{CMG}}; '''Associate | {{CMG}}; '''Associate Editor(s)-In-Chief:''' [[User:Mohammed Sbeih|Mohammed A. Sbeih, M.D.]] [mailto:msbeih@wikidoc.org]; {{LG}}; {{USAMA}} '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@elon.edu] | ||
==Overview== | ==Overview== | ||
Aortic stenosis is a major health problem primarily | [[Aortic stenosis]] is a major health problem that primarily affects the elderly. The majority of cases of aortic stenosis is due to [[calcific aortic valve disease|calcific]] [[degeneration]]. [[Aortic stenosis]] tends to affect approximately 1% of patients over the age of 65, 2% of patients over the age of 75, and 4% of patients over the age 85.<ref name="pmid9060903">{{cite journal |author=Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM |title=Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study |journal=[[Journal of the American College of Cardiology]] |volume=29 |issue=3 |pages=630–4 |year=1997 |month=March |pmid=9060903 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0735109796005633 |accessdate=2012-04-11}}</ref> As North American and European populations continue to live longer, aortic stenosis has major public health implications. Abnormalities of aortic valve morphology and function represent the most common valvular lesion in the elderly.<ref name="pmid8712130">{{cite journal| author=Iivanainen AM, Lindroos M, Tilvis R, Heikkilä J, Kupari M| title=Natural history of aortic valve stenosis of varying severity in the elderly. | journal=Am J Cardiol | year= 1996 | volume= 78 | issue= 1 | pages= 97-101 | pmid=8712130 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8712130 }} </ref> | ||
==Prevalence== | ==Epidemiology and Demographics== | ||
===Prevalence=== | |||
*The prevalence of aortic stenosis is approximately 3% in adults over 75 years.<ref name="pmid27582763">{{cite journal| author=Carità P, Coppola G, Novo G, Caccamo G, Guglielmo M, Balasus F | display-authors=etal| title=Aortic stenosis: insights on pathogenesis and clinical implications. | journal=J Geriatr Cardiol | year= 2016 | volume= 13 | issue= 6 | pages= 489-98 | pmid=27582763 | doi=10.11909/j.issn.1671-5411.2016.06.001 | pmc=4987417 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27582763 }} </ref> | |||
*According to the Cardiovascular Health Study, the [[prevalence]] of aortic stenosis among patients more than 65 years of age is approximately 2% in the United States.<ref name="pmid9060903">{{cite journal |author=Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM |title=Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study |journal=[[Journal of the American College of Cardiology]] |volume=29 |issue=3 |pages=630–4 |year=1997 |month=March |pmid=9060903 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0735109796005633 |accessdate=2012-04-11}}</ref> | |||
*Based on the results from the EuroHeart Failure survey programme, 4.8% of patients with [[acute coronary syndrome]] had significant valve disease, in particular [[calcific aortic valve disease|calcific]] [[aortic stenosis]].<ref name="pmid12633546">{{cite journal |author=Cleland JG, Swedberg K, Follath F, Komajda M, Cohen-Solal A, Aguilar JC, Dietz R, Gavazzi A, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, van Gilst WH, Widimsky J, Freemantle N, Eastaugh J, Mason J |title=The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis |journal=[[European Heart Journal]] |volume=24 |issue=5 |pages=442–63 |year=2003 |month=March |pmid=12633546 |doi= |url=http://eurheartj.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=12633546 |accessdate=2012-04-11}}</ref> | |||
===Age=== | |||
The [[prevalence]] of [[aortic stenosis]] increases with age. Less than 1% of all live births exhibit [[symptoms]] of [[severe aortic stenosis]]. Approximately 1% of patients over the age of 65, 2% of patients over the age of 75, and 4% of patients over the age of 85 have [[aortic stenosis]].<ref name="pmid9060903">{{cite journal |author=Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM |title=Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study |journal=[[Journal of the American College of Cardiology]] |volume=29 |issue=3 |pages=630–4 |year=1997 |month=March |pmid=9060903 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0735109796005633 |accessdate=2012-04-11}}</ref><ref name="pmid8459080">{{cite journal |author=Lindroos M, Kupari M, Heikkilä J, Tilvis R |title=Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample |journal=[[Journal of the American College of Cardiology]] |volume=21 |issue=5 |pages=1220–5 |year=1993 |month=April |pmid=8459080 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/0735-1097(93)90249-Z |accessdate=2012-04-11}}</ref> | |||
===Gender=== | |||
Calcific degenerative aortic stenosis is more common in males.<ref>Townsend CM, et al. Sabiston Textbook of Surgery. 18th ed. Saunders; 2008:1841-1844.</ref> | |||
In | ===Developed Countries=== | ||
In North America and Europe, a linear relationship exists between the increase in the [[incidence]] of [[aortic stenosis]] and the increase in aging population.<ref name="pmid25140960">{{cite journal| author=Otto CM, Prendergast B| title=Aortic-valve stenosis--from patients at risk to severe valve obstruction. | journal=N Engl J Med | year= 2014 | volume= 371 | issue= 8 | pages= 744-56 | pmid=25140960 | doi=10.1056/NEJMra1313875 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25140960 }} </ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[CME Category::Cardiology]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Valvular heart disease]] | [[Category:Valvular heart disease]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Congenital heart disease]] | [[Category:Congenital heart disease]] | ||
[[Category: | [[Category:Cardiac surgery]] | ||
[[Category:Surgery]] | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Mohammed A. Sbeih, M.D. [2]; Lakshmi Gopalakrishnan, M.B.B.S. [3]; Usama Talib, BSc, MD [4] Assistant Editor-In-Chief: Kristin Feeney, B.S. [5]
Overview
Aortic stenosis is a major health problem that primarily affects the elderly. The majority of cases of aortic stenosis is due to calcific degeneration. Aortic stenosis tends to affect approximately 1% of patients over the age of 65, 2% of patients over the age of 75, and 4% of patients over the age 85.[1] As North American and European populations continue to live longer, aortic stenosis has major public health implications. Abnormalities of aortic valve morphology and function represent the most common valvular lesion in the elderly.[2]
Epidemiology and Demographics
Prevalence
- The prevalence of aortic stenosis is approximately 3% in adults over 75 years.[3]
- According to the Cardiovascular Health Study, the prevalence of aortic stenosis among patients more than 65 years of age is approximately 2% in the United States.[1]
- Based on the results from the EuroHeart Failure survey programme, 4.8% of patients with acute coronary syndrome had significant valve disease, in particular calcific aortic stenosis.[4]
Age
The prevalence of aortic stenosis increases with age. Less than 1% of all live births exhibit symptoms of severe aortic stenosis. Approximately 1% of patients over the age of 65, 2% of patients over the age of 75, and 4% of patients over the age of 85 have aortic stenosis.[1][5]
Gender
Calcific degenerative aortic stenosis is more common in males.[6]
Developed Countries
In North America and Europe, a linear relationship exists between the increase in the incidence of aortic stenosis and the increase in aging population.[7]
References
- ↑ 1.0 1.1 1.2 Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM (1997). "Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study". Journal of the American College of Cardiology. 29 (3): 630–4. PMID 9060903. Retrieved 2012-04-11. Unknown parameter
|month=ignored (help) - ↑ Iivanainen AM, Lindroos M, Tilvis R, Heikkilä J, Kupari M (1996). "Natural history of aortic valve stenosis of varying severity in the elderly". Am J Cardiol. 78 (1): 97–101. PMID 8712130.
- ↑ Carità P, Coppola G, Novo G, Caccamo G, Guglielmo M, Balasus F; et al. (2016). "Aortic stenosis: insights on pathogenesis and clinical implications". J Geriatr Cardiol. 13 (6): 489–98. doi:10.11909/j.issn.1671-5411.2016.06.001. PMC 4987417. PMID 27582763.
- ↑ Cleland JG, Swedberg K, Follath F, Komajda M, Cohen-Solal A, Aguilar JC, Dietz R, Gavazzi A, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, van Gilst WH, Widimsky J, Freemantle N, Eastaugh J, Mason J (2003). "The EuroHeart Failure survey programme-- a survey on the quality of care among patients with heart failure in Europe. Part 1: patient characteristics and diagnosis". European Heart Journal. 24 (5): 442–63. PMID 12633546. Retrieved 2012-04-11. Unknown parameter
|month=ignored (help) - ↑ Lindroos M, Kupari M, Heikkilä J, Tilvis R (1993). "Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample". Journal of the American College of Cardiology. 21 (5): 1220–5. PMID 8459080. Retrieved 2012-04-11. Unknown parameter
|month=ignored (help) - ↑ Townsend CM, et al. Sabiston Textbook of Surgery. 18th ed. Saunders; 2008:1841-1844.
- ↑ Otto CM, Prendergast B (2014). "Aortic-valve stenosis--from patients at risk to severe valve obstruction". N Engl J Med. 371 (8): 744–56. doi:10.1056/NEJMra1313875. PMID 25140960.