Hemophilia echocardiography or ultrasound: Difference between revisions

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{{CMG}};{{AE}} {{Sab}}
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==Overview==
==Overview==
There are no echocardiography findings associated with hemophilia. Ultrasound may be helpful in the diagnosis and follow-up of hemophilic arthropathy and in diagnosing massive intraabdominal bleeds. Findings on ultrasound suggestive of hemophilic arthropathy inlcude soft-tissue changes, osteochondral changes, joint effusion, synovial hypertrophy, hemosiderin, and osteochondral abnormalities.
There are no [[echocardiography]] findings associated with hemophilia. [[Ultrasound]] may be helpful in the [[diagnosis]] and follow-up of [[Hemophilia|hemophilic]] [[arthropathy]] and in [[Diagnosis|diagnosing]] massive [[Abdomen|intraabdominal]] [[Bleeding|bleeds]]. Findings on an [[ultrasound]] suggestive of [[Hemophilia|hemophilic]] [[arthropathy]] inlcude [[Soft tissue|soft-tissue]] changes, [[Bone|osteo]]-[[Cartilage|chondral]] changes, [[joint]] effusion, [[synovial]] [[Hypertrophy (medical)|hypertrophy]], [[hemosiderin]], and [[Bone|osteo]]-[[Cartilage|chondral]] abnormalities.


==Echocardiography/Ultrasound==
==Echocardiography/Ultrasound==
===Echocardiography===
===Echocardiography===
There are no echocardiography findings associated with hemophilia.
There are no [[echocardiography]] findings associated with hemophilia.
===Ultrasound===
===Ultrasound===
*Ultrasound may be helpful in the diagnosis and follow-up of hemophilic arthropathy and in diagnosing massive intraabdominal bleeds
*[[Ultrasound]] may be helpful in the [[diagnosis]] and follow-up of [[Hemophilia|hemophilic]] [[arthropathy]] and in [[Diagnosis|diagnosing]] massive [[Abdomen|intraabdominal]] [[Bleeding|bleeds]]
*Ultrasound is highly reliable for assessing soft-tissue changes with an intraclass correlation coefficient (ICC) for specific joints given below:
*[[Ultrasound]] is highly reliable for assessing [[Soft tissue|soft-tissue]] changes with an intraclass correlation coefficient (ICC) for specific [[Joint|joints]] given below:
:*0.98 for ankles<ref name="pmid25714320">{{cite journal |vauthors=Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S |title=Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation |journal=AJR Am J Roentgenol |volume=204 |issue=3 |pages=W336–47 |date=March 2015 |pmid=25714320 |doi=10.2214/AJR.14.12501 |url=}}</ref>
:*0.98 for [[Ankle|ankles]]<ref name="pmid25714320">{{cite journal |vauthors=Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S |title=Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation |journal=AJR Am J Roentgenol |volume=204 |issue=3 |pages=W336–47 |date=March 2015 |pmid=25714320 |doi=10.2214/AJR.14.12501 |url=}}</ref>
:*0.97 for knees
:*0.97 for [[Knee|knees]]
*Ultrasound is substantially to highly reliable for assessing osteochondral changes with an intraclass correlation coefficient (ICC) for specific joints given below:
*[[Ultrasound]] is substantially to highly reliable for assessing [[Bone|osteo]]-[[Cartilage|chondral]] changes with an intraclass correlation coefficient (ICC) for specific [[Joint|joints]] given below:
:*0.61 for ankles<ref name="pmid25714320">{{cite journal |vauthors=Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S |title=Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation |journal=AJR Am J Roentgenol |volume=204 |issue=3 |pages=W336–47 |date=March 2015 |pmid=25714320 |doi=10.2214/AJR.14.12501 |url=}}</ref>
:*0.61 for [[Ankle|ankles]]<ref name="pmid25714320">{{cite journal |vauthors=Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S |title=Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation |journal=AJR Am J Roentgenol |volume=204 |issue=3 |pages=W336–47 |date=March 2015 |pmid=25714320 |doi=10.2214/AJR.14.12501 |url=}}</ref>
:*0.89 for knees
:*0.89 for [[Knee|knees]]
*It is highly sensitive (> 92%) for assessing synovial hypertrophy and hemosiderin in both ankles and knees<ref name="pmid25714320">{{cite journal |vauthors=Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S |title=Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation |journal=AJR Am J Roentgenol |volume=204 |issue=3 |pages=W336–47 |date=March 2015 |pmid=25714320 |doi=10.2214/AJR.14.12501 |url=}}</ref>
*It is highly [[Sensitivity (tests)|sensitive]] (> 92%) for assessing [[synovial]] [[Hypertrophy (medical)|hypertrophy]] and [[hemosiderin]] in both [[Ankle|ankles]] and [[Knee|knees]]<ref name="pmid25714320">{{cite journal |vauthors=Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S |title=Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation |journal=AJR Am J Roentgenol |volume=204 |issue=3 |pages=W336–47 |date=March 2015 |pmid=25714320 |doi=10.2214/AJR.14.12501 |url=}}</ref>
*It has borderline sensitivity for detecting small amounts of fluid in ankles (70%) in contrast to knees (93%)
*It has borderline [[Sensitivity (tests)|sensitivity]] for detecting small amounts of [[fluid]] in [[Ankle|ankles]] (70%) in contrast to [[Knee|knees]] (93%)
*It has variable sensitivity for evaluating osteochondral abnormalities (86-100% for ankles and 12-100% for knees)
*It has variable [[Sensitivity (tests)|sensitivity]] for evaluating [[Bone|osteo]]-[[Cartilage|chondral]] abnormalities (86-100% for [[Ankle|ankles]] and 12-100% for [[Knee|knees]])


==References==
==References==

Latest revision as of 01:29, 23 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

There are no echocardiography findings associated with hemophilia. Ultrasound may be helpful in the diagnosis and follow-up of hemophilic arthropathy and in diagnosing massive intraabdominal bleeds. Findings on an ultrasound suggestive of hemophilic arthropathy inlcude soft-tissue changes, osteo-chondral changes, joint effusion, synovial hypertrophy, hemosiderin, and osteo-chondral abnormalities.

Echocardiography/Ultrasound

Echocardiography

There are no echocardiography findings associated with hemophilia.

Ultrasound

  • Ultrasound is substantially to highly reliable for assessing osteo-chondral changes with an intraclass correlation coefficient (ICC) for specific joints given below:

References

  1. 1.0 1.1 1.2 Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S (March 2015). "Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation". AJR Am J Roentgenol. 204 (3): W336–47. doi:10.2214/AJR.14.12501. PMID 25714320.

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