Omphalocele

(Redirected from Coelosomia)
Jump to navigation Jump to search
https://https://www.youtube.com/watch?v=1vaoR8HYJxI%7C350}}
Omphalocele
ICD-10 Q79.2
ICD-9 756.79
OMIM 164750
DiseasesDB 23647
eMedicine rad/483 
MeSH D006554

WikiDoc Resources for Omphalocele

Articles

Most recent articles on Omphalocele

Most cited articles on Omphalocele

Review articles on Omphalocele

Articles on Omphalocele in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Omphalocele

Images of Omphalocele

Photos of Omphalocele

Podcasts & MP3s on Omphalocele

Videos on Omphalocele

Evidence Based Medicine

Cochrane Collaboration on Omphalocele

Bandolier on Omphalocele

TRIP on Omphalocele

Clinical Trials

Ongoing Trials on Omphalocele at Clinical Trials.gov

Trial results on Omphalocele

Clinical Trials on Omphalocele at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Omphalocele

NICE Guidance on Omphalocele

NHS PRODIGY Guidance

FDA on Omphalocele

CDC on Omphalocele

Books

Books on Omphalocele

News

Omphalocele in the news

Be alerted to news on Omphalocele

News trends on Omphalocele

Commentary

Blogs on Omphalocele

Definitions

Definitions of Omphalocele

Patient Resources / Community

Patient resources on Omphalocele

Discussion groups on Omphalocele

Patient Handouts on Omphalocele

Directions to Hospitals Treating Omphalocele

Risk calculators and risk factors for Omphalocele

Healthcare Provider Resources

Symptoms of Omphalocele

Causes & Risk Factors for Omphalocele

Diagnostic studies for Omphalocele

Treatment of Omphalocele

Continuing Medical Education (CME)

CME Programs on Omphalocele

International

Omphalocele en Espanol

Omphalocele en Francais

Business

Omphalocele in the Marketplace

Patents on Omphalocele

Experimental / Informatics

List of terms related to Omphalocele

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

An omphalocele is a type of abdominal wall defect in which the intestines, liver, and occasionally other organs remain outside of the abdomen in a sac because of a defect in the development of the muscles of the abdominal wall.

Causes

Some cases of omphalocele are believed to be due to an underlying genetic disorder.[1][2]

Congenital conditions

  • Pentalogy of Cantrell

Chromosomal abnormalities

  • Wiedemann-Beckwith syndrome

Mendelian inherited conditions

  • Opitz-Frias syndrome
  • Osteodysplasty (Melnick-Needles)

Autosomal recessive conditions

  • Donnai-Barrow syndrome
  • Manitoba oculotrichoanal syndrome

Presentation

The sac protrudes in the midline, through the umbilicus (navel).

It is normal for the intestines to protrude from the abdomen, into the umbilical cord, until about the tenth week of pregnancy, after which they return to inside the fetal abdomen.

The omphalocele can be mild, with only a small loop of intestines present outside the abdomen, or severe, containing most of the abdominal organs. In severe cases surgical treatment is made more difficult because the infant's abdomen is abnormally small because it had no need to expand to accommodate the developing organs.

Screening

An omphalocele is often detected through AFP screening or a detailed fetal ultrasound. Genetic counseling and genetic testing such as amniocentesis is usually offered during the pregnancy. Some cases of omphalocele are due to an underlying genetic disorder.

Related conditions

Gastroschisis is a similar birth defect, but the umbilical cord is not involved, and parts of organs may be in the amniotic fluid, and not enclosed in a membranous sac.

Examples

References

  1. Kanagawa SL, Begleiter ML, Ostlie DJ, Holcomb G, Drake W, Butler MG (2002). "Omphalocele in three generations with autosomal dominant transmission". J. Med. Genet. 39 (3): 184–5. doi:10.1136/jmg.39.3.184. PMID 11897819.
  2. Yatsenko SA, Mendoza-Londono R, Belmont JW, Shaffer LG (2003). "Omphalocele in trisomy 3q: further delineation of phenotype". Clin. Genet. 64 (5): 404–13. doi:10.1034/j.1399-0004.2003.00159.x. PMID 14616763.

External links




de:Omphalozele


Template:WikiDoc Sources