Thymoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2]
Overview
Signs and symptoms
30% of patients with a thymoma have symptoms caused by compression of the surrounding organs, these symptoms may include:[1]
- Facial swelling (due to compression of the upper caval vein)
- Dysphagia (due to compression of the esophagus)
- Cough and wheezing (due to compression of the trachea)
- Chest pain (due to local compression of the mass itself)
30% of patients have their tumors discovered because they have an associated autoimmune disorder, these symptoms may include:
- Muscle weakness (associated with myasthenia gravis and polymyositis)
- Anemia (associated with pure red cell aplasia)
- Fever, chest pain, cough and malaise (associated with Good's syndrome, agranulocytosis, combined immunodeficiency, hypogammaglobulinemia and acute pericarditis)
- Arthralgia and rash (associated with polymyositis, scleroderma, rheumatoid arthritis and systemic lupus erythematosus)
- Anxiety, diarrhea and palpitation (associated with thyroiditis and ulcerative colitis)
Asymptoms
33% to 50% of patients with thymoma have no symptoms at all, and the mass is identified on a chest X-ray performed for an unrelated problems.[1]
References
- ↑ 1.0 1.1 Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter
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