Thymoma history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Symptoms of thymoma include [[muscle weakness]], [[cough]], [[wheezing]], and [[dysphagia]] in addition to the symptoms of associated immune syndromes such as [[anemia]], [[arthralgia]], and [[skin rash]]. | [[Symptom|Symptoms]] of thymoma include [[muscle weakness]], [[cough]], [[wheezing]], and [[dysphagia|difficulty swallowing]] in addition to the [[Symptom|symptoms]] of associated [[Immune disorder|immune syndromes]] such as [[anemia]], [[arthralgia]], and [[skin rash]]. | ||
== | ==History and Symptoms== | ||
===Symptoms | ===Symptoms of [[Mass effect (medicine)|Mass Effect]]=== | ||
Approximately 30% of patients with thymoma have symptoms caused by compression of the surrounding organs, these may include:<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | Approximately 30% of the [[patients]] with thymoma have [[Symptom|symptoms]] caused by compression of the surrounding [[Organ (anatomy)|organs]], these may include:<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | ||
* Facial swelling (due to compression of the [[vena cava | *[[Facial]] [[swelling]] (due to compression of the [[superior vena cava]]) | ||
*[[Dysphagia]] (due to compression of the [[esophagus]]) | *[[Dysphagia|Difficulty swallowing]] (due to compression of the [[esophagus]]) | ||
*[[Cough]] and [[wheezing]] (due to compression of the [[trachea]]) | *[[Cough]] and [[wheezing]] (due to compression of the [[trachea]]) | ||
*[[Chest pain]] (due to local compression | *[[Chest pain]] (due to local compression) | ||
===Symptoms | ===Symptoms Related to Associated Autoimmune Diseases=== | ||
Approximately 30% of patients have symptoms of associated autoimmune disorders, these may include: | Approximately 30% of the [[Patient|patients]] have [[symptoms]] of associated [[autoimmune disorders]], these may include: | ||
*[[Muscle weakness]] (associated with [[myasthenia gravis]] and [[polymyositis]]) | *[[Muscle weakness]] (associated with [[myasthenia gravis]] and [[polymyositis]]) | ||
*[[Anemia]] (associated with [[pure red cell aplasia]]) | *[[Anemia]] (associated with [[pure red cell aplasia]]) | ||
*[[Fever]], [[chest pain]], [[cough]] and [[malaise]] (associated with [[Good's syndrome]], [[agranulocytosis]], [[combined immunodeficiency]], [[hypogammaglobulinemia]] and acute [[pericarditis]]) | *[[Fever]], [[chest pain]], [[cough]], and [[malaise]] (associated with [[Good's syndrome]], [[agranulocytosis]], [[combined immunodeficiency]], [[hypogammaglobulinemia]], and [[acute]] [[pericarditis]]) | ||
*[[Arthralgia]] and [[skin rash]] (associated with [[polymyositis]], [[scleroderma]], [[rheumatoid arthritis]] and [[systemic lupus erythematosus]]) | *[[Arthralgia]] and [[skin rash]] (associated with [[polymyositis]], [[scleroderma]], [[rheumatoid arthritis]], and [[systemic lupus erythematosus]]) | ||
*[[Anxiety]], diarrhea and palpitation (associated with [[thyroiditis]] and [[ulcerative colitis]]) | *[[Anxiety]], [[diarrhea]] and [[palpitation]] (associated with [[thyroiditis]] and [[ulcerative colitis]]) | ||
===Asymptomatic=== | ===Asymptomatic=== | ||
Approximately 33% to 50% of patients with thymoma have no symptoms at all, and the mass is identified incidentally.<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | Approximately 33% to 50% of the [[Patient|patients]] with thymoma have no [[symptoms]] at all, and the mass is identified [[Incidental finding|incidentally]].<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | ||
==References== | ==References== | ||
Latest revision as of 19:32, 14 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2] Ahmad Al Maradni, M.D. [3]
Overview
Symptoms of thymoma include muscle weakness, cough, wheezing, and difficulty swallowing in addition to the symptoms of associated immune syndromes such as anemia, arthralgia, and skin rash.
History and Symptoms
Symptoms of Mass Effect
Approximately 30% of the patients with thymoma have symptoms caused by compression of the surrounding organs, these may include:[1]
- Facial swelling (due to compression of the superior vena cava)
- Difficulty swallowing (due to compression of the esophagus)
- Cough and wheezing (due to compression of the trachea)
- Chest pain (due to local compression)
Symptoms Related to Associated Autoimmune Diseases
Approximately 30% of the patients have symptoms of associated autoimmune disorders, these may include:
- Muscle weakness (associated with myasthenia gravis and polymyositis)
- Anemia (associated with pure red cell aplasia)
- Fever, chest pain, cough, and malaise (associated with Good's syndrome, agranulocytosis, combined immunodeficiency, hypogammaglobulinemia, and acute pericarditis)
- Arthralgia and skin rash (associated with polymyositis, scleroderma, rheumatoid arthritis, and systemic lupus erythematosus)
- Anxiety, diarrhea and palpitation (associated with thyroiditis and ulcerative colitis)
Asymptomatic
Approximately 33% to 50% of the patients with thymoma have no symptoms at all, and the mass is identified incidentally.[1]
References
- ↑ 1.0 1.1 Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter
|month=ignored (help)