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==Overview==
==Overview==
[[Symptom|Symptoms]] of thymoma include [[muscle weakness]], [[cough]], [[wheezing]], and [[dysphagia|difficulty swallowing]] in addition to the [[Symptom|symptoms]] of associated [[Immune disorder|immune syndromes]] such as [[anemia]], [[arthralgia]], and [[skin rash]].


==Signs and symptoms==
==History and Symptoms==
{{Seealso|Myasthenia gravis}}
===Symptoms of [[Mass effect (medicine)|Mass Effect]]===
===Symptoms related to mass compression===
Approximately 30% of the [[patients]] with thymoma have [[Symptom|symptoms]] caused by compression of the surrounding [[Organ (anatomy)|organs]], these may include:<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>
30% of patients with a thymoma have symptoms caused by compression of the surrounding organs, these symptoms may include:<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>
*[[Facial]] [[swelling]] (due to compression of the [[superior vena cava]])
 
*[[Dysphagia|Difficulty swallowing]] (due to compression of the [[esophagus]])
* Facial swelling (due to compression of the [[vena cava superior|upper caval vein]])
*[[Dysphagia]] (due to compression of the [[esophagus]])
*[[Cough]] and [[wheezing]] (due to compression of the [[trachea]])
*[[Cough]] and [[wheezing]] (due to compression of the [[trachea]])
*[[Chest pain]] (due to local compression of the mass itself)
*[[Chest pain]] (due to local compression)
===Sympotms related to associated autoimmune diseases===
30% of patients have their tumors discovered because they have an associated autoimmune disorder, these symptoms may include:
*Muscle weakness (associated with [[myasthenia gravis]] and [[polymyositis]])
*Anemia (associated with [[pure red cell aplasia]])
*Fever, chest pain, cough and malaise (associated with [[Good's syndrome]], [[agranulocytosis]], [[combined immunodeficiency]], [[hypogammaglobulinemia]] and acute [[pericarditis]])  )
*Arthralgia and rash (associated with [[polymyositis]], [[scleroderma]], [[rheumatoid arthritis]] and [[systemic lupus erythematosus]])


*Anexity, diarrhea and palpitation (associated with [[thyroiditis]] and [[ulcerative colitis]])
===Symptoms Related to Associated Autoimmune Diseases===
Approximately 30% of the [[Patient|patients]] have [[symptoms]] of associated [[autoimmune disorders]], these may include:
*[[Muscle weakness]] (associated with [[myasthenia gravis]] and [[polymyositis]])
*[[Anemia]] (associated with [[pure red cell aplasia]])
*[[Fever]], [[chest pain]], [[cough]], and [[malaise]] (associated with [[Good's syndrome]], [[agranulocytosis]], [[combined immunodeficiency]], [[hypogammaglobulinemia]], and [[acute]] [[pericarditis]])
*[[Arthralgia]] and [[skin rash]] (associated with [[polymyositis]], [[scleroderma]], [[rheumatoid arthritis]], and [[systemic lupus erythematosus]])
*[[Anxiety]], [[diarrhea]] and [[palpitation]] (associated with [[thyroiditis]] and [[ulcerative colitis]])


===Asymptoms===
===Asymptomatic===
33% to 50% of patients with thymoma have no symptoms at all, and the mass is identified on a [[chest X-ray]] performed for an unrelated problems.<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>
Approximately 33% to 50% of the [[Patient|patients]] with thymoma have no [[symptoms]] at all, and the mass is identified [[Incidental finding|incidentally]].<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref>


==References==
==References==
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Latest revision as of 19:32, 14 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [2] Ahmad Al Maradni, M.D. [3]

Overview

Symptoms of thymoma include muscle weakness, cough, wheezing, and difficulty swallowing in addition to the symptoms of associated immune syndromes such as anemia, arthralgia, and skin rash.

History and Symptoms

Symptoms of Mass Effect

Approximately 30% of the patients with thymoma have symptoms caused by compression of the surrounding organs, these may include:[1]

Symptoms Related to Associated Autoimmune Diseases

Approximately 30% of the patients have symptoms of associated autoimmune disorders, these may include:

Asymptomatic

Approximately 33% to 50% of the patients with thymoma have no symptoms at all, and the mass is identified incidentally.[1]

References

  1. 1.0 1.1 Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter |month= ignored (help)

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