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==Overview==
==Overview==


Squamous cell carcinoma of the lung accounts for 30-35% of all lung cancers, and is the second most commonly encountered lung cancer, after lung adenocarcinoma.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref> Squamous cell carcinoma of the lung accounts for about 27.4% of all cancer deaths. The incidence of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] increases with age; the [[median]] age at diagnosis is 70 years.<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref> Squamous cell carcinoma is most frequently diagnosed among people among 65 to 74 years old. Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1. Squamous cell carcinoma of the lung usually affects black individuals more frequently. Black race has a higher incidence compared to the white race to develop squamous cell lung carcinoma.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers. It is the second most commonly encountered lung cancer after lung adenocarcinoma.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref> Squamous cell carcinoma of the lung accounts for approximately 27% of all cancer deaths. The incidence of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] increases with age; the [[median]] age at diagnosis is approximately 70 years (usually ranging from 65 to 74 years).<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref> Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1. Black race has a higher incidence of squamous cell lung carcinoma compared with White race.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>


==Epidemiology and Demographics==
==Epidemiology and Demographics==


===Prevalence===
===Prevalence===
* Squamous cell carcinoma of the lung is the second most common non-small cell lung cancer subtype in the United States
* Squamous cell carcinoma of the lung is the second most common non-small cell lung cancer subtype in the United States.
* Squamous cell carcinoma of the lung accounts for 30-35% of all lung cancers
* Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers.
* Squamous cell carcinoma of the lung accounts for about 27.4% of all cancer deaths<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
* Squamous cell carcinoma of the lung accounts for approximately 27% of all cancer deaths.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
===Incidence===
===Incidence===
* The incidence rate of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] is 14.4 per 100,000 individuals a year
* The annual incidence rate of [[Squamous-cell carcinoma|lung squamous cell carcinoma]] is 14.4 per 100,000 individuals.
* The relative incidence rate of squamous cell carcinoma of the lung appears to be decreasing, compared to previous years<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
* The relative incidence rate of squamous cell carcinoma of the lung appears to be decreasing, compared to previous years.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
===Age===
===Age===
* The incidence of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] increases with age; the [[median]] age at diagnosis is 70 years<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref>
* The incidence of [[Squamous-cell carcinoma|lung squamous-cell carcinoma]] increases with age; the [[median]] age at diagnosis is 70 years (usually ranging from 65 to 74 years).<ref name="pmid19934774">{{cite journal |vauthors=Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R |title=Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis |journal=J Thorac Oncol |volume=5 |issue=1 |pages=23–8 |year=2010 |pmid=19934774 |doi=10.1097/JTO.0b013e3181c41e8d |url=}}</ref>
* Squamous cell carcinoma is most frequently diagnosed among people among 55 to 60 years or older<ref name="pmid16436765">{{cite journal |vauthors=Haiman CA, Stram DO, Wilkens LR, Pike MC, Kolonel LN, Henderson BE, Le Marchand L |title=Ethnic and racial differences in the smoking-related risk of lung cancer |journal=N. Engl. J. Med. |volume=354 |issue=4 |pages=333–42 |year=2006 |pmid=16436765 |doi=10.1056/NEJMoa033250 |url=}}</ref>


===Gender===
===Gender===
*Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1
*Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1.
===Race===
===Race===
*Squamous cell carcinoma of the lung usually affects black individuals more frequently. Black race has a higher incidence compared to the white race to develop squamous cell lung carcinoma<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>
*Black race has a higher incidence of squamous cell lung carcinoma compared with White race.<ref name="pmid25822850">{{cite journal |vauthors=Meza R, Meernik C, Jeon J, Cote ML |title=Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010 |journal=PLoS ONE |volume=10 |issue=3 |pages=e0121323 |year=2015 |pmid=25822850 |pmc=4379166 |doi=10.1371/journal.pone.0121323 |url=}}</ref>


==References==
==References==

Revision as of 19:13, 25 April 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2] Maria Fernanda Villarreal, M.D. [3]

Overview

Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers. It is the second most commonly encountered lung cancer after lung adenocarcinoma.[1] Squamous cell carcinoma of the lung accounts for approximately 27% of all cancer deaths. The incidence of lung squamous-cell carcinoma increases with age; the median age at diagnosis is approximately 70 years (usually ranging from 65 to 74 years).[2] Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1. Black race has a higher incidence of squamous cell lung carcinoma compared with White race.[1]

Epidemiology and Demographics

Prevalence

  • Squamous cell carcinoma of the lung is the second most common non-small cell lung cancer subtype in the United States.
  • Squamous cell carcinoma of the lung accounts for 30% to 35% of all lung cancers.
  • Squamous cell carcinoma of the lung accounts for approximately 27% of all cancer deaths.[1]

Incidence

  • The annual incidence rate of lung squamous cell carcinoma is 14.4 per 100,000 individuals.
  • The relative incidence rate of squamous cell carcinoma of the lung appears to be decreasing, compared to previous years.[1]

Age

Gender

  • Males are more commonly affected with squamous cell carcinoma of the lung than females. The male to female ratio is approximately 1.8 to 1.

Race

  • Black race has a higher incidence of squamous cell lung carcinoma compared with White race.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 Meza R, Meernik C, Jeon J, Cote ML (2015). "Lung cancer incidence trends by gender, race and histology in the United States, 1973-2010". PLoS ONE. 10 (3): e0121323. doi:10.1371/journal.pone.0121323. PMC 4379166. PMID 25822850.
  2. 2.0 2.1 Subramanian J, Morgensztern D, Goodgame B, Baggstrom MQ, Gao F, Piccirillo J, Govindan R (2010). "Distinctive characteristics of non-small cell lung cancer (NSCLC) in the young: a surveillance, epidemiology, and end results (SEER) analysis". J Thorac Oncol. 5 (1): 23–8. doi:10.1097/JTO.0b013e3181c41e8d. PMID 19934774.


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