Sickle-cell disease history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shyam Patel [2]

Overview

Symptoms of sickle-cell disease include mild pain in the arms an legs to severe pain from sickle cell crises and acute chest syndrome.

History

The location of vaso-occlusive episodes determines the types of symptoms a patient will experience. For example, vaso-occlusive crisis in the bones will cause bone pain. Bones, especially weight-bearing bones, are a common target of vaso-occlusive damage due to bone ischemia.

Symptoms

Symptoms of sickle-cell disease include:

Acute chest crisis

In addition to the symptoms above, symptoms of acute chest crisis include:

References