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{{Seminoma}}
{{Seminoma}}
{{CMG}}
{{CMG}}
==Overview==
==[[Seminoma overview|Overview]]==
'''Seminoma''' is one type of [[testicular cancer]]<ref>{{Dorlands|s_07|12728548}}</ref> that is believed to originate from the [[germinal epithelium]] of the [[seminiferous tubule]]s.


==Presentation==
==[[Seminoma historical perspective|Historical Perspective]]==
They produce bulky masses that can be up to ten times the size of a normal testis.
 
==[[Seminoma pathophysiology|Pathophysiology]]==
 
==[[Seminoma causes|Causes]]==
 
==[[Seminoma differential diagnosis|Differentiang Seminoma from other Diseases]]==
 
==[[Seminoma epidemiology and demographics|Epidemiology and Demographics]]==
 
==[[Seminoma risk factors|Risk Factors]]==
 
==[[Seminoma screening|Screening]]==
 
==[[Seminoma natural history, complications and prognosis|Natural History, Complications and Prognosis]]==


==Diagnosis==
==Diagnosis==
{{Gene|POU2AF1}} and {{Gene|PROM1}} have been proposed as possible markers.<ref name="pmid17785371">{{cite journal |author=Gashaw I, Dushaj O, Behr R, ''et al'' |title=Novel germ cell markers characterize testicular seminoma and fetal testis |journal=Mol. Hum. Reprod. |volume=13 |issue=10 |pages=721–7 |year=2007 |pmid=17785371 |doi=10.1093/molehr/gam059}}</ref>


Peak incidence occurs in the 4th decade of life.  Histology shows large cells, clear sytoplasm, distinct cell membranes, and septated arcitecture.
[[Seminoma history and symptoms|History & Symptoms]] | [[Seminoma physical examination|Physical Examination]] | [[Seminoma laboratory findings|Laboratory Findings]] | [[Seminoma electrocardiogram|Electrocardiogram]] | [[Seminoma chest x ray|Chest X Ray]] | [[Seminoma CT|CT]] | [[Seminoma MRI|MRI]] | [[Seminoma ultrasound|Ultrasound]] | [[Seminoma other imaging findings|Other Imaging Findings]] | [[Seminoma other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
In recent years, these tumors have been shown to have dramatic sensitivity to both [[radiotherapy]] and [[cytotoxic]] [[chemotherapy]]. The management of childhood seminoma is similar to that of adult seminoma. [[Orchiectomy]] is required in almost all cases.
 
[[Seminoma medical therapy|Medical Therapy]] | [[Seminoma surgery|Surgery]] | [[Seminoma primary prevention|Primary Prevention]] | [[Seminoma secondary prevention|Secondary Prevention]] | [[Seminoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Seminoma future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
 
[[Seminoma case study one|Case #1]]
 


==References==
==References==

Revision as of 15:47, 11 September 2012


For patient information click here.

Seminoma
ICD-10 C62
ICD-9 186
ICD-O: 9061
OMIM 273300
DiseasesDB 12966
MedlinePlus 001288
MeSH D018239

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Historical Perspective

Pathophysiology

Causes

Differentiang Seminoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History & Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1


References

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