Seminoma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

Based on the histology, testicular seminoma may be classified into three subtypes: classic, anaplastic, and spermatocytic.

Classification

Based on the histology, testicular seminoma may be classified into three subtypes:

• Classic: 85%, infrequent mitoses, monotonous sheet of large cells with abundant cytoplasm and round hyperchromatic nuclei, prominent nucleoli
• Anaplastic: 10%, 3 or more mitotic figures per high-power field
• Spermatocytic: 5%, older male patients above 60 years old, rarely metastasise; well-differentiated with cells resembling secondary spermatids