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==Overview==
==Overview==

Revision as of 19:55, 10 September 2012

Seminoma
ICD-10 C62
ICD-9 186
ICD-O: 9061
OMIM 273300
DiseasesDB 12966
MeSH D018239

Seminoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Seminoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

TNM
Stage Grouping

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Treatment - Stage I
Treatment - Stage II
Treatment - Stage III
Treatment - Recurrent

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Seminoma On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Seminoma

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Seminoma

CDC on Seminoma

Seminoma in the news

Blogs on Seminoma

Directions to Hospitals Treating Seminoma

Risk calculators and risk factors for Seminoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Seminoma is one type of testicular cancer[1] that is believed to originate from the germinal epithelium of the seminiferous tubules.

Presentation

They produce bulky masses that can be up to ten times the size of a normal testis.

Diagnosis

POU2AF1 and PROM1 have been proposed as possible markers.[2]

Peak incidence occurs in the 4th decade of life. Histology shows large cells, clear sytoplasm, distinct cell membranes, and septated arcitecture.

Treatment

In recent years, these tumors have been shown to have dramatic sensitivity to both radiotherapy and cytotoxic chemotherapy. The management of childhood seminoma is similar to that of adult seminoma. Orchiectomy is required in almost all cases.

References

  1. Template:Dorlands
  2. Gashaw I, Dushaj O, Behr R; et al. (2007). "Novel germ cell markers characterize testicular seminoma and fetal testis". Mol. Hum. Reprod. 13 (10): 721–7. doi:10.1093/molehr/gam059. PMID 17785371.

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