Scrotal mass differential diagnosis: Difference between revisions

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|[[Leukocytosis]]

Revision as of 19:58, 23 January 2019

Scrotal Mass Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Scrotal masses may be differentiated according to clinical features, laboratory findings, imaging features, histological features, and genetic studies from other diseases that cause testicular mass with discomfort, back pain, abdominal discomfort, or abdominal mass. Common differential diagnoses include yolk sac tumor, teratoma, choriocarcinoma, embryonal cell carcinoma, seminoma, and testicular lymphoma (usually non-Hodgkin lymphoma).

Differential Diagnosis

The table below summarizes the findings that differentiates scrotal mass according to the clinical features, laboratory findings, imaging features, histological features, and genetic studies.

Scrotal Swelling Diseases Clinical manifestations Para-clinical findings Gold standard Associated
Painful Symptoms Physical examination
Lab Findings Past Medical History Histopathology
Unilateral /Bilateral swelling Onset Fever Urinary symptoms Tenderness Erythema Discharge Inguinal Lymphadenopathy Cremasteric Reflex Urine Analysis Doppler U/S
Epididymitis[1] Unilateral Gradual ± Dysuria, frequency, and/or urgency + _ Pyuria Painful local lymphadenopathy +

Leukocytosis

Enlarged (>17 mm) epididymis with a hypoechoic, hyperechoic, or heterogeneous echotexture, increased blood flow Hydrocele
Orchitis Unilateral or bilateral Abrupt ± Dysuria + - ± Painful local lymphadenopathy + Leukocytosis
Testicular Torsion[2] Unilateral Sudden - + + Blood in semen - Normal Absent or decreased arterial perfusion of the testis
Torsion of testicular appendix Unilateral Sudden - + + - - Normal Absent or decreased arterial perfusion of the testis prepubertal period
Hematocele Unilateral or bilateral Sudden - + + Blood in semen
Incarcerated Hernia[3][4] Unilateral Sudden + - + + - Absent
Testicular Abcess -
Brucellosis -
Histoplasma
Gonorrhea
Fournier's gangrene
Scrotal Swelling Diseases Unilateral /Bilateral swelling Onset Fever Urinary symptoms Tenderness Erythema Discharge Inguinal Lymphadenopathy Cremasteric Reflex Urine Analysis Doppler U/S Past Medical History Histopathology Gold standard Additional findings
Painless Fragile XMacroorchidism Bilateral - +
Testicular Tumors ± +
Henoch-Schonlein purpura - -
Hydrocele[5] Gradual _ - - - Ultrasound:

simple fluid collection

Varicocele[6] Unilateral

(Mainly left)

Gradual Local warmth - ± - Absent Ultrasonography:

tortuous, tubular, anechoic structures adjacent to the testis corresponding to dilated veins of the pampiniform plexus with calibers of 2–3 mm during the Valsalva maneuver

Spermatocele[7] Gradual - - - Absent
  • Falling snow, resulting from internal echoes moving away from the transducer
Ultrasonography:

hypoechoic with posterior acoustic enhancement

Inguino-scrotal hernia[8][3] - - Absent
Scrotal edema - -
Epididymal cyst[9] ± Ultrasonography::

posterior acoustic enhancement, well defined anechoic lesions, larger cysts may contain septations

Scrotal oedema
Sebaceous cyst
Carcinoma of the scrotum
Chylocele (Filariasis)
Cystic dysplasia
Srotoliths

References

  1. Yu KJ, Wang TM, Chen HW, Wang HH (2012). "The dilemma in the diagnosis of acute scrotum: clinical clues for differentiating between testicular torsion and epididymo-orchitis". Chang Gung Med J. 35 (1): 38–45. PMID 22483426.
  2. Gunther P, Schenk JP, Wunsch R, Holland-Cunz S, Kessler U, Troger J, Waag KL (November 2006). "Acute testicular torsion in children: the role of sonography in the diagnostic workup". Eur Radiol. 16 (11): 2527–32. doi:10.1007/s00330-006-0287-1. PMID 16724203.
  3. 3.0 3.1 Jenkins JT, O'Dwyer PJ (2008). "Inguinal hernias". BMJ. 336 (7638): 269–72. doi:10.1136/bmj.39450.428275.AD. PMC 2223000. PMID 18244999.
  4. Berger D (2016). "Evidence-Based Hernia Treatment in Adults". Dtsch Arztebl Int. 113 (9): 150–7, quiz 158. doi:10.3238/arztebl.2016.0150. PMC 4802357. PMID 26987468.
  5. Yang DM, Kim HC, Lim JW, Jin W, Ryu CW, Kim GY, Cho H (2007). "Sonographic findings of groin masses". J Ultrasound Med. 26 (5): 605–14. PMID 17460003.
  6. Yang DM, Kim HC, Lim JW, Jin W, Ryu CW, Kim GY, Cho H (2007). "Sonographic findings of groin masses". J Ultrasound Med. 26 (5): 605–14. PMID 17460003.
  7. Yang DM, Kim HC, Lim JW, Jin W, Ryu CW, Kim GY, Cho H (2007). "Sonographic findings of groin masses". J Ultrasound Med. 26 (5): 605–14. PMID 17460003.
  8. Berger D (2016). "Evidence-Based Hernia Treatment in Adults". Dtsch Arztebl Int. 113 (9): 150–7, quiz 158. doi:10.3238/arztebl.2016.0150. PMC 4802357. PMID 26987468.
  9. Yang DM, Kim HC, Lim JW, Jin W, Ryu CW, Kim GY, Cho H (2007). "Sonographic findings of groin masses". J Ultrasound Med. 26 (5): 605–14. PMID 17460003.