Pelvic inflammatory disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]

Overview

There is no specific laboratory findings for PID. Elevated ESR and CRP are suggestive for diagnosis but are not specific. NAAT for N. gonorrhoeae and C. trachomatis must be requested.

Laboratory findings

  • There is no specific laboratory findings for PID. Elevated CRP and ESR are non specific findings. Leukocytosis is another findings.
  • Laboratory confirmation of Chlamydia, Gonorrhea and/or Mycoplasma genitalium in cervical discharge is helpful to guide treatment.[1]
  • All patients with suspected pelvic inflammatory disease should undergo cervical or vaginal nucleic acid amplification tests for N. gonorrhoeae and C. trachomatis infection.[2]
  • Vaginal fluid should be evaluated for increased numbers of white cells (more than one neutrophil per epithelial cell) and signs of bacterial vaginosis.[2]
  • Pregnancy test should be routinely requested to help rule out ectopic pregnancy.
  • Serologic testing for human immunodeficiency virus (HIV) should be performed.[2]

References

  1. Workowski KA, Bolan GA (2015). "Sexually transmitted diseases treatment guidelines, 2015". MMWR Recomm Rep. 64 (RR-03): 1–137. PMID 26042815.
  2. 2.0 2.1 2.2 Brunham RC, Gottlieb SL, Paavonen J (2015). "Pelvic inflammatory disease". N. Engl. J. Med. 372 (21): 2039–48. doi:10.1056/NEJMra1411426. PMID 25992748.

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