Pancreatic fistula history and symptoms: Difference between revisions
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==Overview== | |||
A [[pancreatic]] [[fistula]] with leakage of fluid can be diagnosed in some cases with typical history and clinical presentation, such as patient presenting with [[pancreatitis]] followed by recurrence, persistent symptoms or post [[pancreatic]] [[resection]] fluid drainage with increase [[amylase]] level. Patients diagnosed with [[pancreatic]] [[fistula]] are sometimes [[asymptomatic]] while some patients may present with [[symptoms]] such as marked recent [[weight loss]], unresponsiveness of the [[ascites]] to [[diuretics]], non-specific symptoms such as [[nausea]], [[vomiting]], [[hypotension]], [[infection]], and [[tachycardia]] and some patients with a high grade [[fistula]] may present with [[sepsis]] | |||
==History and Symptoms== | |||
===History=== | |||
== | *A [[pancreatic]] [[fistula]] with leakage of fluid can be diagnosed in some cases with typical history and clinical presentation, such as patient presenting with [[pancreatitis]] followed by recurrence, persistent symptoms or post [[pancreatic]] [[resection]] fluid drainage with increase [[amylase]] level.<ref name="pmid32809706">{{cite journal| author=| title=StatPearls | journal= | year= 2021 | volume= | issue= | pages= | pmid=32809706 | doi= | pmc= | url= }}</ref><ref name="JohnstonPrew2013">{{cite journal|last1=Johnston|first1=M. J.|last2=Prew|first2=C. L.|last3=Fraser|first3=I.|title=An unusual case of pancreatic fistula|journal=Journal of Surgical Case Reports|volume=2013|issue=3|year=2013|pages=rjt014–rjt014|issn=2042-8812|doi=10.1093/jscr/rjt014}}</ref> | ||
*However, most cases are far more challenging which require [[imaging]] techniques and examination of the fluid samples withdrawn from the leak to help diagnose the [[fistula]].<ref name="pmid24650171">{{cite journal| author=Larsen M, Kozarek R| title=Management of pancreatic ductal leaks and fistulae. | journal=J Gastroenterol Hepatol | year= 2014 | volume= 29 | issue= 7 | pages= 1360-70 | pmid=24650171 | doi=10.1111/jgh.12574 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24650171 }} </ref> | |||
== | ===Symptoms=== | ||
Patients diagnosed with [[pancreatic]] [[fistula]] are sometimes [[asymptomatic]] while some patients may have the following [[symptoms]]:<ref name="pmid24650171">{{cite journal| author=Larsen M, Kozarek R| title=Management of pancreatic ductal leaks and fistulae. | journal=J Gastroenterol Hepatol | year= 2014 | volume= 29 | issue= 7 | pages= 1360-70 | pmid=24650171 | doi=10.1111/jgh.12574 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24650171 }} </ref> | |||
*[[Anorexia]], [[weakness]] and [[malnutrition]] presenting as marked recent [[weight loss]] | |||
* | *Unresponsiveness of the [[ascites]] to [[diuretics]] | ||
* Unresponsiveness of the ascites to diuretics | *Non-specific symptoms such as [[nausea]], [[vomiting]], [[hypotension]], [[infection]], and [[tachycardia]] | ||
*Some patients with a high grade [[fistula]] may present with [[sepsis]] | |||
*Patients with external [[pancreatic fistula]] may present with marked [[skin]] excoriations visible around the [[fistula]] site. | |||
*Patients with thoracopancreatic [[fistula]] may present with symptoms of [[cough]], [[wheezing]], [[Shortness of breath|dyspnea]], [[chest pain]] and [[Palpitation|palpitations]]. On [[Chest X-ray|chest x ray]], there may be incidental finding of unilateral or [[bilateral]] [[pleural effusion]]. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 11:14, 10 April 2021
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Pancreatic fistula Microchapters |
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Pancreatic fistula history and symptoms On the Web |
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Risk calculators and risk factors for Pancreatic fistula history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
A pancreatic fistula with leakage of fluid can be diagnosed in some cases with typical history and clinical presentation, such as patient presenting with pancreatitis followed by recurrence, persistent symptoms or post pancreatic resection fluid drainage with increase amylase level. Patients diagnosed with pancreatic fistula are sometimes asymptomatic while some patients may present with symptoms such as marked recent weight loss, unresponsiveness of the ascites to diuretics, non-specific symptoms such as nausea, vomiting, hypotension, infection, and tachycardia and some patients with a high grade fistula may present with sepsis
History and Symptoms
History
- A pancreatic fistula with leakage of fluid can be diagnosed in some cases with typical history and clinical presentation, such as patient presenting with pancreatitis followed by recurrence, persistent symptoms or post pancreatic resection fluid drainage with increase amylase level.[1][2]
- However, most cases are far more challenging which require imaging techniques and examination of the fluid samples withdrawn from the leak to help diagnose the fistula.[3]
Symptoms
Patients diagnosed with pancreatic fistula are sometimes asymptomatic while some patients may have the following symptoms:[3]
- Anorexia, weakness and malnutrition presenting as marked recent weight loss
- Unresponsiveness of the ascites to diuretics
- Non-specific symptoms such as nausea, vomiting, hypotension, infection, and tachycardia
- Some patients with a high grade fistula may present with sepsis
- Patients with external pancreatic fistula may present with marked skin excoriations visible around the fistula site.
- Patients with thoracopancreatic fistula may present with symptoms of cough, wheezing, dyspnea, chest pain and palpitations. On chest x ray, there may be incidental finding of unilateral or bilateral pleural effusion.
References
- ↑ "StatPearls". 2021. PMID 32809706 Check
|pmid=value (help). - ↑ Johnston, M. J.; Prew, C. L.; Fraser, I. (2013). "An unusual case of pancreatic fistula". Journal of Surgical Case Reports. 2013 (3): rjt014–rjt014. doi:10.1093/jscr/rjt014. ISSN 2042-8812.
- ↑ 3.0 3.1 Larsen M, Kozarek R (2014). "Management of pancreatic ductal leaks and fistulae". J Gastroenterol Hepatol. 29 (7): 1360–70. doi:10.1111/jgh.12574. PMID 24650171.