Orbital cellulitis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Overview

Orbital cellulitis must be differentiated from preseptal cellulitis.

Differential Diagnosis

Orbital cellulitis may share common features or present similarly to other eye diseases with significantly varying management protocols. As such, the clinician must carefully consider the patient's history, the presenting signs and symptoms, and cross reference the following differentials:^[1]^[2]

Infectious diseases

Periorbital cellulitis
Endophthalmitis
Severe conjunctivitis
Herpes Zoster Ophthalmicus
Posterior Scleritis
Mucormycosis, Aspergilliosis of the globe
M.Tuberculosis of the globe

Vascular

Cavernous sinus thrombosis
Atriovenous fistula
Orbital varices

Autoimmune/Inflammatory

Exophthalmos
Wegeners granulomatosis
Sarcoidosis granuloma
Orbital pseudotumor

Structural/Trauma

Toxicity

Bisphosphanate use

Neoplastic

References

↑ American Academy of Ophthalmology EyeWiki (2015)http://eyewiki.aao.org/Orbital_Cellulitis#Differential_Diagnosis-
↑ Lam Choi VB, Yuen HK, Biswas J, Yanoff M (2011). "Update in pathological diagnosis of orbital infections and inflammations". Middle East Afr J Ophthalmol. 18 (4): 268–76. doi:10.4103/0974-9233.90127. PMC 3249811. PMID 22224014.

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[eyewikiorbitalcellulitis-1] American Academy of Ophthalmology EyeWiki (2015)http://eyewiki.aao.org/Orbital_Cellulitis#Differential_Diagnosis-

[pmid22224014-2] Lam Choi VB, Yuen HK, Biswas J, Yanoff M (2011). "Update in pathological diagnosis of orbital infections and inflammations". Middle East Afr J Ophthalmol. 18 (4): 268–76. doi:10.4103/0974-9233.90127. PMC 3249811. PMID 22224014.

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