Orbital cellulitis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]


In 1882, Dr. Nettleship, a British surgeon, described orbital cellulitis in a case study.[1] In 1937, Dr. Davis reported a review of 54 successfully treated patients and suggested a management guideline for orbital cellulitis.

Historical Perspective

  • In 1882, Dr. Nettleship, a British surgeon, described orbital cellulitis in a case study.[1]
  • In 1892, Dr. E.E. Holt first described orbital cellulitis as a case study in the literature. He hypothesized that orbital cellulitis was a result of extension of an adjacent infection. In his work, Dr. Holt references the work of Dr. Nettleship.[1]
  • In 1935, Dr. T.B. Layton outlines a surgical approach to treatment by simple incision, drainage, and irrigation of the retro-orbital space.[2]
  • In 1937, the procedure created by Dr. Layton was confirmed in a review of 54 successfully treated cases of orbital cellulitis by Dr. Davis.[3]


  1. 1.0 1.1 1.2 Holt EE (1892). "Orbital Cellulitis, the inflammation spreading to the temporal region, to the neck, obstructing deglutition, and to the brain, causing death, with reports of five other cases". Trans Am Ophthalmol Soc. 6: 295–306. PMC 1326882. PMID 25259124.
  2. Layton TB (1935). "Four Cases of Orbital Cellulitis Secondary to Nasal Disease Treated by Simple Incision". Proc R Soc Med. 28 (12): 1569–71. PMC 2205946. PMID 19990471.
  3. "Orbital Cellulitis due to Sinus Infection, and its Treatment: (Section of Laryngology and Section of Otology)". Proc R Soc Med. 30 (11): 1397–407. 1937. PMC 2076505. PMID 19991275.

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