Merkel cell cancer classification

Revision as of 13:08, 20 August 2015 by Ahmad Al Maradni (talk | contribs)
Jump to navigation Jump to search

Merkel cell cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Merkel Cell Cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

CT

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Merkel cell cancer classification On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Merkel cell cancer classification

All Images
X-rays
Echo and Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Merkel cell cancer classification

CDC on Merkel cell cancer classification

Merkel cell cancer classification in the news

Blogs on Merkel cell cancer classification

Directions to Hospitals Treating Merkel cell cancer

Risk calculators and risk factors for Merkel cell cancer classification

Classification

Histologically, MCC has been classified into three distinct subtypes:

  • Trabecular: classic pattern, large-cell type, high density or granules on ultrasound examination.
  • Intermediate: solid pattern (most common).
  • Small cell: diffuse, few high density granules on ultrasound examination (second most common).

Staging

Stage Primary Tumor Lymph Node Metastasis
0 In situ primary tumor No regional lymph node metastasis No distant metastasis
IA Less than or equal to 2 cm maximum tumor dimension Nodes negative by pathologic exam No distant metastasis
IB Less than or equal to 2 cm maximum tumor dimension Nodes negative by clinical exam* (no pathologic node exam performed) No distant metastasis
IIA Greater than 2 cm tumor dimension Nodes negative by pathologic exam No distant metastasis
IIB Greater than 2 cm tumor dimension Nodes negative by clinical exam* (no pathologic node exam performed) No distant metastasis
IIC Primary tumor invades bone, muscle, fascia, or cartilage No regional lymph node metastasis No distant metastasis
IIIA Any size tumor (includes invading tumors) Micrometastasis** No distant metastasis
IIIB Any size tumor (includes invading tumors) "Macrometastasis*** -OR- In transit metastasis****" No distant metastasis
IV Any size tumor (includes invading tumors) Any lymph node metastasis Metastasis beyond regional lymph nodes

References