Lymphoplasmacytic lymphoma (patient information): Difference between revisions

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* Swollen/[[enlarged liver]]
* Swollen/[[enlarged liver]]
* Swollen/[[enlarged lymph nodes]]
* Swollen/[[enlarged lymph nodes]]
* An [[eye]] exam may show enlarged [[veins]] in the [[retina]] or [[retinal bleeding]] ([[hemorrhages]]).
* An [[eye]] exam may show enlarged [[veins]] in the [[retina]] or [[retinal bleeding]] ([[hemorrhages]])


Tests may include:
Tests may include:


* [[Complete blood count]] ([[CBC]]) - shows a low number of [[red blood cells]] and [[platelets|platelets.]]
* [[Complete blood count]] ([[CBC]]) - shows a low number of [[red blood cells]] and [[platelets|platelets]]
* [[Blood chemistry tests|Blood chemistry]] - evidence of [[kidney disease]].
* [[Blood chemistry tests|Blood chemistry]] - evidence of [[kidney disease]]
* Serum [[viscosity]] test.
* Serum [[viscosity]] test
* [[Serum protein electrophoresis]] - increased amount of the [[IgM]] [[antibody]]. Levels seen in [[Waldenström's macroglobulinemia|Waldenstrom's macroglobulinemia]] are generally greater than 3 g/dL.
* [[Serum protein electrophoresis]] - increased amount of the [[IgM]] [[antibody]]. Levels seen in [[Waldenström's macroglobulinemia|Waldenstrom's macroglobulinemia]] are generally greater than 3 g/dL
* [[Bone marrow examination]] - show cells that resemble both [[lymphocytes]] and [[plasma cells]].
* [[Bone marrow examination]] - show cells that resemble both [[lymphocytes]] and [[plasma cells]]


Additional tests that may be done:
Additional tests that may be done:

Revision as of 21:02, 20 February 2019

Lymphoplasmacytic lymphoma

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Lymphoplasmacytic lymphoma?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Lymphoplasmacytic lymphoma On the Web

Ongoing Trials at Clinical Trials.gov

Images of Lymphoplasmacytic lymphoma

Videos on Lymphoplasmacytic lymphoma

FDA on Lymphoplasmacytic lymphoma

CDC on Lymphoplasmacytic lymphoma

Lymphoplasmacytic lymphoma in the news

Blogs on Lymphoplasmacytic lymphoma

Directions to Hospitals Treating Lymphoplasmacytic lymphoma

Risk calculators and risk factors for Lymphoplasmacytic lymphoma

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Overview

Lymphoplasmacytic lymphoma is a cancer of the B lymphocytes (a type of white blood cell). It is associated with the overproduction of proteins called IgM antibodies.

What are the symptoms of lymphoplasmacytic lymphoma?

Following are the common symptoms observed in patients with lymphoplasmacytic lymphoma:[1]

Additional symptoms that may be associated with this disease:

What causes lymphoplasmacytic lymphoma?

Lymphoplasmacytic lymphoma is a result of a condition called Waldenstrom macroglobulinemia. The cause of the overproduction of the IgM antibody is unknown, but researchers believe it is made by lymphoma cells.

Overproduction of IgM causes the blood to become too thick. This is called hyperviscosity. It occasionally makes it harder for blood to flow through small blood vessels.

About 1,500 people in the United States are diagnosed with lymphoplasmacytic lymphoma every year. Most people with this condition are over age 65; however, it may also occur in younger people.

Diagnosis

Signs may include:

Tests may include:

Additional tests that may be done:

When to seek urgent medical care?

Call your health care provider if any symptoms of this disorder develop.

Treatment

What to expect (Outlook/Prognosis)?

The average survival is about 6.5 years. Some people live more than 10 years. In some people, LPL may produce few symptoms and progress slowly.

Possible complications

Sources

  1. "Macroglobulinemia of Waldenstrom: MedlinePlus Medical Encyclopedia".