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==Overview==
==Overview==


The hallmark symptoms of lung mass, include: [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]], [[Asbestosis|exposure to asbestos]], [[tuberculosis infection]], or a [[Occupational safety and health|high risk occupation]] may be suggestive of a lung mass. Symptoms related with lung mass will vary depending upon the size and location of tumor. Common symptoms of lung mass may also include [[shortness of breath]], [[fatigue]], and [[chest pain]].<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref><ref name="pmid17505036">{{cite journal |vauthors=Raz DJ, Zell JA, Ou SH, Gandara DR, Anton-Culver H, Jablons DM |title=Natural history of stage I non-small cell lung cancer: implications for early detection |journal=Chest |volume=132 |issue=1 |pages=193–9 |year=2007 |pmid=17505036 |doi=10.1378/chest.06-3096 |url=}}</ref>
The [[hallmark]] [[Symptom|symptoms]] of lung mass include [[Cough|chronic cough]], [[weight loss]], and [[hemoptysis]]. A positive history of [[smoking]], [[Asbestosis|exposure to asbestos]], [[tuberculosis infection]], or a [[Occupational safety and health|high risk occupation]] may be suggestive of a lung mass. [[Symptom|Symptoms]] related to lung mass will vary depending upon the size and location of [[tumor]]. Common [[Symptom|symptoms]] of lung mass may also include [[shortness of breath]], [[fatigue]], and [[chest pain]].
 
==History and Symptoms==
 
=== History ===
 
*Specific areas of focus when obtaining the history are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref>


==History==
*Obtaining the [[History and Physical examination|history]] is an important aspect of making the [[Diagnosis-related group|diagnosis]] of lung mass. Complete history will help determine the likelihood of [[malignancy]], and the association with other conditions. Specific symptoms description such as duration, onset, and progression are important for making the diagnosis. Specific areas of focus when obtaining the history, are outlined below:<ref name="pmid11899115">{{cite journal |vauthors=Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J |title=The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study |journal=Cancer Causes Control |volume=13 |issue=1 |pages=27–34 |year=2002 |pmid=11899115 |doi= |url=}}</ref>
:*[[Age]]
:*[[Age]]
:*Family history of [[cancer]]
:*[[Family history]] of [[cancer]]
:*Personal history of [[cancer]]  
:*Personal history of [[cancer]]
:*Positive history of active/[[passive smoking]]
:*Positive history of active/[[passive smoking]]
::*Number of cigarettes/year  
::*Number of [[Cigarette|cigarettes]]/year
::*Number of years/months of active smoking
::*Number of years/months of [[Smoking|active smoking]]
::*Number of years/months of second-hand smoking  
::*Number of years/months of [[Passive smoking|second-hand smoking]]
::*Number of years/months of [[smoking cessation]]  
::*Number of years/months since [[smoking cessation]]
:*Previous primary infection of [[tuberculosis]]
:*Previous primary [[infection]] of [[tuberculosis]]
:*Onset of pulmonary symptoms
:*Onset of [[Lung|pulmonary]] [[Symptom|symptoms]]
::*Acute (< 6 weeks)  
::*[[Acute (medicine)|Acute]] (< 6 weeks)
::*Chronic (> 6 weeks)
::*[[Chronic (medical)|Chronic]] (> 6 weeks)
:*Previous or current lung disease, such as:  
:*Previous or current [[lung disease]], such as:
::*[[Chronic obstructive pulmonary disease]]
::*[[Chronic obstructive pulmonary disease]]
::*[[Interstitial lung disease]]
::*[[Interstitial lung disease]]
*Several patient factors may influence the likelihood of a [[benign]] versus a [[malignant]] condition; these include previous exposure to smoke or other [[carcinogen]]s such as [[asbestos]], and previously diagnosed cancer or [[respiratory infection]]s. A patient with airway symptoms, especially [[hemoptysis]], is more likely to have [[cancer]] compared to a patient with no respiratory symptoms.


==Common Symptoms==
*Several [[patient]] factors may influence the likelihood of a [[benign]] versus a [[malignant]] condition; these include previous exposure to [[smoke]] or other [[carcinogen]]s such as [[asbestos]], and previously [[Diagnosis|diagnosed]] [[cancer]] or [[respiratory infection]]s.
*The majority of lung masses are [[asymptomatic]] and are usually found incidentally.<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref>
*A [[patient]] with [[airway]] [[Symptom|symptoms]], especially [[hemoptysis]], is more likely to have [[cancer]] compared to a [[patient]] with no [[respiratory]] [[Symptom|symptoms]].


=== Common symptoms ===
=== Common symptoms ===
When present, the characteristic symptoms of lung mass include:
*Chronic [[cough]]
*[[Weight loss]]
*[[Hemoptysis]]


===Less common symptoms===  
* The majority of lung masses are [[asymptomatic]] and are usually found incidentally.<ref name="pain">Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016 </ref>
Other symptoms which suggest presence of lung mass include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>
 
:* [[Dyspnea]]
* When present, the characteristic [[Symptom|symptoms]] of lung mass include:
:* [[Wheezing]]
 
:* [[Chest pain]]
**[[Chronic cough]]
:* [[Abdominal pain]]
**[[Weight loss]]
:* [[Cachexia]]
**[[Hemoptysis]]
:* [[Fatigue]]
 
:* Loss of [[appetite]]
===Less Common Symptoms===  
:* [[Dysphonia]]
Other [[Symptom|symptoms]] which suggest the presence of lung mass include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors =  Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref><ref name="canadian">Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015</ref>


==Prognosis==
:*[[Dyspnea|Difficulty breathing]]
*Patients with lung [[adenocarcinomas]] from [[EGFR]] mutations have a more favourable [[prognosis]] when treated with chemotherapy ([[tyrosine kinase inhibitors]] or TKIs).
:*[[Wheezing]]
*The use of TKIs have been observed with significantly longer [[remission]] and higher survival rates as compared to patients lacking [[mutation]] in [[EGFR]].
:*[[Chest pain]]
:*[[Abdominal pain]]
:*[[Cachexia|Weakness and wasting of the body]]
:*[[Fatigue]]
:*[[Anorexia|Loss of appetite]]
:*[[Dysphonia|Difficulty in speaking]]


==References==
==References==

Latest revision as of 17:16, 26 June 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

The hallmark symptoms of lung mass include chronic cough, weight loss, and hemoptysis. A positive history of smoking, exposure to asbestos, tuberculosis infection, or a high risk occupation may be suggestive of a lung mass. Symptoms related to lung mass will vary depending upon the size and location of tumor. Common symptoms of lung mass may also include shortness of breath, fatigue, and chest pain.

History and Symptoms

History

  • Specific areas of focus when obtaining the history are outlined below:[1]

Common symptoms

  • The majority of lung masses are asymptomatic and are usually found incidentally.[2]
  • When present, the characteristic symptoms of lung mass include:

Less Common Symptoms

Other symptoms which suggest the presence of lung mass include:[3][4]

References

  1. Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
  2. Non small cell lung cancer. Wikipedia. https://en.wikipedia.org/wiki/Non-small-cell_lung_carcinoma Accessed on February 24, 2016
  3. Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter |coauthors= ignored (help)
  4. Lung cancer. Canadian Cancer Society 2015. http://www.cancer.ca/en/cancer-information/cancer-type/lung/signs-and-symptoms/?region=ab Accessed on February 24, 2015


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