Lepirudin (injection): Difference between revisions

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==Overview==
==Overview==
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[[Category:Drugs]]
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Revision as of 16:50, 9 August 2012

Lepirudin (injection)
Clinical data
Pregnancy
category
  • US: B (No risk in non-human studies)
Routes of
administration
SQ or IV
ATC code
Pharmacokinetic data
Bioavailability100%
Elimination half-life~1.3 hours
ExcretionRenal
Identifiers
CAS Number
DrugBank
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC288H448N80O110S6
Molar mass6983.5 g/mol

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Experimental / Informatics

List of terms related to Lepirudin (injection)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Lepirudin (Refludan ®) is an anticoagulant which functions as a direct thrombin inhibitor.

It is derived from the saliva of the medicinal leech Hirudo medicinalis.

External links

  • Hirudo Medicinalis TURKEY, Supplier of Hirudo Medicinalis
  • Hirudo Medicinalis TURKEY
  • Template:DiseasesDB
  • Smythe M, Stephens J, Koerber J, Mattson J (2005). "A comparison of lepirudin and argatroban outcomes". Clin Appl Thromb Hemost. 11 (4): 371–4. PMID 16244762.
  • "Predictive factors for thrombosis and major bleeding in an observational study in 181 patients with heparin-induced thrombocytopenia treated with lepirudin". Blood. PMID 16690967.
  • Lubenow N, Eichler P, Lietz T, Greinacher A (2005). "Lepirudin in patients with heparin-induced thrombocytopenia - results of the third prospective study (HAT-3) and a combined analysis of HAT-1, HAT-2, and HAT-3". J Thromb Haemost. 3 (11): 2428–36. PMID 16241940.
  • http://www.refludan.com/product/index.htm


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