Phenprocoumon

Phenprocoumon

Clinical data
ATC code	B01AA04 (WHO)
Pharmacokinetic data
Protein binding	99%
Metabolism	hepatic to inactive metabolites
Elimination half-life	5 to 6 days
Identifiers
IUPAC name 2-hydroxy-3-(1-phenylpropyl)chromen-4-one
CAS Number	435-97-2
PubChem CID	9908
DrugBank	APRD00228
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C18H16O3
Molar mass	280.318 g/mol

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Evidence Based Medicine
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Clinical Trials
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Definitions
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Patient Resources / Community
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Experimental / Informatics
List of terms related to Phenprocoumon

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Phenprocoumon (marketed under the brand names Marcoumar, Marcumar and Falithrom) is a long-acting oral anticoagulant drug, a derivative of coumarin. It is a vitamin K antagonist that inhibits coagulation by blocking synthesis of coagulation factors II, VII, IX and X. It is used for the prophylaxis and treatment of thromboembolic disorders (thrombosis/pulmonary embolism). It is the standard coumarin used in Germany.

Phenprocoumon is a 4-hydroxycoumarin and inhibits vitamin K epoxide reductase.

External Links

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