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{{Irritable bowel syndrome}}
{{Irritable bowel syndrome}}
{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{Cherry}}
==Overview==
==Overview==
 
[[Irritable bowel syndrome|Irritable bowel syndrome (IBS)]] may be classified according to Rome IV [[Criterion|criteria]] into [[Irritable bowel syndrome|IBS]] with predominant [[constipation]] , [[Irritable bowel syndrome|IBS]] with predominant [[diarrhea]], [[Irritable bowel syndrome|IBS]] with mixed [[Bowel|bowel habits]], and unclassified [[Irritable bowel syndrome|IBS]]. In addition, [[Irritable bowel syndrome|IBS]] occurring subsequent to [[gastrointestinal]] [[Infection|infections]] is known as post [[Infection|infectious]]-IBS (PI-[[Irritable bowel syndrome|IBS]]). The rationale behind these different sub-types is to maintain consistency of [[patient]] selection. This increases understanding of [[Pathophysiology|pathophysiological]] mechanisms, aids in effective [[diagnosis]], [[Treatment Planning|treatment]], and patient recruitment for [[Clinical trial|clinical trials]].
[[Irritable bowel syndrome|Irritable bowel syndrome (IBS)]] may be classified according to Rome IV criteria into four subtypes/groups: [[Irritable bowel syndrome|IBS]] with predominant [[constipation]] , [[Irritable bowel syndrome|IBS]] with predominant [[diarrhea]], [[Irritable bowel syndrome|IBS]] with mixed bowel habits,and [[Irritable bowel syndrome|IBS]] unclassified. In addition, [[Irritable bowel syndrome|IBS]] occuring subsequent to GI [[Infection|infections]] is known as PI-IBS or post infectious [[Irritable bowel syndrome|IBS]].<ref name="pmid15862928">{{cite journal |vauthors=Longstreth GF |title=Definition and classification of irritable bowel syndrome: current consensus and controversies |journal=Gastroenterol. Clin. North Am. |volume=34 |issue=2 |pages=173–87 |year=2005 |pmid=15862928 |doi=10.1016/j.gtc.2005.02.011 |url=}}</ref>


==Classification==
==Classification==
Irritable bowel syndrome (IBS) may be classified according to Rome IV criteria into 4 subtypes based on predominant stool type:<ref name="pmid25731138">{{cite journal |vauthors=Sayuk GS, Gyawali CP |title=Irritable bowel syndrome: modern concepts and management options |journal=Am. J. Med. |volume=128 |issue=8 |pages=817–27 |year=2015 |pmid=25731138 |doi=10.1016/j.amjmed.2015.01.036 |url=}}</ref><ref name="pmid26929659">{{cite journal |vauthors=Lacy BE |title=Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome |journal=Int J Gen Med |volume=9 |issue= |pages=7–17 |year=2016 |pmid=26929659 |pmc=4755466 |doi=10.2147/IJGM.S93698 |url=}}</ref>
[[Irritable bowel syndrome|Irritable bowel syndrome (IBS)]] may be classified according to Rome IV [[Criterion|criteria]] into 4 sub-types based on predominant type of [[bowel]] habits:<ref name="pmid15862928">{{cite journal |vauthors=Longstreth GF |title=Definition and classification of irritable bowel syndrome: current consensus and controversies |journal=Gastroenterol. Clin. North Am. |volume=34 |issue=2 |pages=173–87 |year=2005 |pmid=15862928 |doi=10.1016/j.gtc.2005.02.011 |url=}}</ref><ref name="pmid25731138">{{cite journal |vauthors=Sayuk GS, Gyawali CP |title=Irritable bowel syndrome: modern concepts and management options |journal=Am. J. Med. |volume=128 |issue=8 |pages=817–27 |year=2015 |pmid=25731138 |doi=10.1016/j.amjmed.2015.01.036 |url=}}</ref><ref name="pmid26929659">{{cite journal |vauthors=Lacy BE |title=Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome |journal=Int J Gen Med |volume=9 |issue= |pages=7–17 |year=2016 |pmid=26929659 |pmc=4755466 |doi=10.2147/IJGM.S93698 |url=}}</ref><ref name="pmid20502449">{{cite journal |vauthors=Wong RK, Palsson OS, Turner MJ, Levy RL, Feld AD, von Korff M, Whitehead WE |title=Inability of the Rome III criteria to distinguish functional constipation from constipation-subtype irritable bowel syndrome |journal=Am. J. Gastroenterol. |volume=105 |issue=10 |pages=2228–34 |year=2010 |pmid=20502449 |pmc=3786710 |doi=10.1038/ajg.2010.200 |url=}}</ref><ref name="pmid10457044">{{cite journal |vauthors=Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Müller-Lissner SA |title=Functional bowel disorders and functional abdominal pain |journal=Gut |volume=45 Suppl 2 |issue= |pages=II43–7 |year=1999 |pmid=10457044 |pmc=1766683 |doi= |url=}}</ref><ref name="pmid12241674">{{cite journal |vauthors=Talley NJ, Spiller R |title=Irritable bowel syndrome: a little understood organic bowel disease? |journal=Lancet |volume=360 |issue=9332 |pages=555–64 |year=2002 |pmid=12241674 |doi=10.1016/S0140-6736(02)09712-X |url=}}</ref>
# [[Irritable bowel syndrome|IBS]] with predominant [[constipation]]
* [[Irritable bowel syndrome|IBS]] with predominant [[constipation]]
# [[Irritable bowel syndrome|IBS]] with predominant [[diarrhea]]
* [[Irritable bowel syndrome|IBS]] with predominant [[diarrhea]]
# [[Irritable bowel syndrome|IBS]] with mixed bowel habits: alternating patterns of stool passage which is not in conjuncture with the normal bowel movements.
* [[Irritable bowel syndrome|IBS]] with mixed [[Intestine|bowel]] habits:  
# [[Irritable bowel syndrome|IBS]] unclassified: Patients who meet the diagnostic criteria for [[Irritable bowel syndrome|IBS]] but whose bowel habits do not fit into any of the above subtypes.
** Alternating patterns of [[stool]] passage which is not in conjuncture with the normal [[Bowel movement|bowel movements]].
* [[Irritable bowel syndrome|IBS]] unclassified:  
** Patients who meet the diagnostic criteria for [[Irritable bowel syndrome|IBS]] but whose bowel habits do not fit into any of the above subtypes.


[[Irritable bowel syndrome|IBS]]-PI or post infectious IBS. It is an additional subtype described that occurs subsequent to infections of the GI tract.
* Post [[Infection|infectious]] IBS (PI-IBS):
** Post-infectious IBS is an additional sub-type that is [[Acute (medicine)|acute]] in onset and occurs subsequent to an [[Infection|infectious]] illness of the [[gastrointestinal tract]]. Post-infectious IBS is characterized by two or more of the following:<ref name="pmid12776965">{{cite journal |vauthors=Holten KB, Wetherington A, Bankston L |title=Diagnosing the patient with abdominal pain and altered bowel habits: is it irritable bowel syndrome? |journal=Am Fam Physician |volume=67 |issue=10 |pages=2157–62 |year=2003 |pmid=12776965 |doi= |url=}}</ref>
*** [[Vomiting]]
*** [[Fever]]
*** Positive [[stool culture]]
*** [[Diarrhea]]
{| class="wikitable"
{| class="wikitable"
!SUBTYPE
! style="background:#4479BA; color: #FFFFFF;" ! |SUBTYPE
!HARD OR LUMPY STOOLS
! style="background:#4479BA; color: #FFFFFF;" ! |HARD OR LUMPY STOOLS
!LOOSE(MUSHY) OR WATERY STOOLS
! style="background:#4479BA; color: #FFFFFF;" ! |LOOSE (MUSHY) OR WATERY STOOLS
|-
|-
|IBS with constipation
| style="background:#DCDCDC;" align="center" |IBS with [[constipation]]
|≥ 25 percent
|≥ 25 percent
| ≤ 25 percent
| ≤ 25 percent
|-
|-
|IBS with diarrhea
| style="background:#DCDCDC;" align="center" |IBS with [[diarrhea]]
| ≤ 25 percent
| ≤ 25 percent
|≥ 25 percent
|≥ 25 percent
|-
|-
|Mixed IBS
| style="background:#DCDCDC;" align="center" |Mixed IBS
|≥ 25 percent
|≥ 25 percent
|≥ 25 percent
|≥ 25 percent
|-
|-
|Unsubtyped IBS
| style="background:#DCDCDC;" align="center" |Unsubtyped IBS
| colspan="2" |Insufficient abnormality of stool consistency to meet criteria for IBS with constipation, diarrhea, or mixed subtypes.
| colspan="2" |Insufficient abnormality of [[Human feces|stool]] consistency to meet criteria for IBS with [[constipation]], [[diarrhea]], or mixed subtypes.
|}
|}



Latest revision as of 22:12, 1 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sudarshana Datta, MD [2]

Overview

Irritable bowel syndrome (IBS) may be classified according to Rome IV criteria into IBS with predominant constipation , IBS with predominant diarrhea, IBS with mixed bowel habits, and unclassified IBS. In addition, IBS occurring subsequent to gastrointestinal infections is known as post infectious-IBS (PI-IBS). The rationale behind these different sub-types is to maintain consistency of patient selection. This increases understanding of pathophysiological mechanisms, aids in effective diagnosis, treatment, and patient recruitment for clinical trials.

Classification

Irritable bowel syndrome (IBS) may be classified according to Rome IV criteria into 4 sub-types based on predominant type of bowel habits:[1][2][3][4][5][6]

  • IBS with predominant constipation
  • IBS with predominant diarrhea
  • IBS with mixed bowel habits:
  • IBS unclassified:
    • Patients who meet the diagnostic criteria for IBS but whose bowel habits do not fit into any of the above subtypes.
SUBTYPE HARD OR LUMPY STOOLS LOOSE (MUSHY) OR WATERY STOOLS
IBS with constipation ≥ 25 percent  ≤ 25 percent
IBS with diarrhea  ≤ 25 percent ≥ 25 percent
Mixed IBS ≥ 25 percent ≥ 25 percent
Unsubtyped IBS Insufficient abnormality of stool consistency to meet criteria for IBS with constipation, diarrhea, or mixed subtypes.

References

  1. Longstreth GF (2005). "Definition and classification of irritable bowel syndrome: current consensus and controversies". Gastroenterol. Clin. North Am. 34 (2): 173–87. doi:10.1016/j.gtc.2005.02.011. PMID 15862928.
  2. Sayuk GS, Gyawali CP (2015). "Irritable bowel syndrome: modern concepts and management options". Am. J. Med. 128 (8): 817–27. doi:10.1016/j.amjmed.2015.01.036. PMID 25731138.
  3. Lacy BE (2016). "Diagnosis and treatment of diarrhea-predominant irritable bowel syndrome". Int J Gen Med. 9: 7–17. doi:10.2147/IJGM.S93698. PMC 4755466. PMID 26929659.
  4. Wong RK, Palsson OS, Turner MJ, Levy RL, Feld AD, von Korff M, Whitehead WE (2010). "Inability of the Rome III criteria to distinguish functional constipation from constipation-subtype irritable bowel syndrome". Am. J. Gastroenterol. 105 (10): 2228–34. doi:10.1038/ajg.2010.200. PMC 3786710. PMID 20502449.
  5. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Müller-Lissner SA (1999). "Functional bowel disorders and functional abdominal pain". Gut. 45 Suppl 2: II43–7. PMC 1766683. PMID 10457044.
  6. Talley NJ, Spiller R (2002). "Irritable bowel syndrome: a little understood organic bowel disease?". Lancet. 360 (9332): 555–64. doi:10.1016/S0140-6736(02)09712-X. PMID 12241674.
  7. Holten KB, Wetherington A, Bankston L (2003). "Diagnosing the patient with abdominal pain and altered bowel habits: is it irritable bowel syndrome?". Am Fam Physician. 67 (10): 2157–62. PMID 12776965.

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