Irritable bowel syndrome other imaging findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sudarshana Datta, MD [2]
Overview
75SeHCAT testing may be helpful in the diagnosis of IBS patients with bile acid diarrhea. The 75SeHCAT test measures the whole-body retention of 75Se-homocholyltaurine, a bile acid radiolabeled with the gamma-emitting isotope selenium-75. Retention of the isotope is measured by gamma-camera scanning performed a week after administration.
Other Imaging Findings
75SeHCAT test
- IBS patients with diarrhea sometimes have bile acid diarrhea on 23-seleno-25-homotaurocholic acid (75SeHCAT) testing.[1]
- The 75SeHCAT test measures the whole-body retention of 75Se-homocholyltaurine, a bile acid radiolabeled with the gamma-emitting isotope selenium-75.
- Retention of the isotope is measured by gamma-camera scanning performed a week after administration.[2][3]
References
- ↑ Slattery SA, Niaz O, Aziz Q, Ford AC, Farmer AD (2015). "Systematic review with meta-analysis: the prevalence of bile acid malabsorption in the irritable bowel syndrome with diarrhoea". Aliment. Pharmacol. Ther. 42 (1): 3–11. doi:10.1111/apt.13227. PMID 25913530.
- ↑ Niaz SK, Sandrasegaran K, Renny FH, Jones BJ (1997). "Postinfective diarrhoea and bile acid malabsorption". J R Coll Physicians Lond. 31 (1): 53–6. PMID 9044199.
- ↑ Williams AJ, Merrick MV, Eastwood MA (1991). "Idiopathic bile acid malabsorption--a review of clinical presentation, diagnosis, and response to treatment". Gut. 32 (9): 1004–6. PMC 1379038. PMID 1916479.