Hypopituitarism history and symptoms: Difference between revisions
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| rowspan="5" |'''Anterior pituitary''' | | rowspan="5" |'''Anterior pituitary''' | ||
|Adrenocorticotrophic Hormone (ACTH) | |Adrenocorticotrophic Hormone (ACTH) | ||
|The most critical hormonal deficient in hypopituitarism.<ref name="Burke1985">{{cite journal|last1=Burke|first1=C.W.|title=Adrenocortical insufficiency|journal=Clinics in Endocrinology and Metabolism|volume=14|issue=4|year=1985|pages=947–976|issn=0300595X|doi=10.1016/S0300-595X(85)80084-0}}</ref> | |The most critical hormonal deficient in hypopituitarism.<ref name="Burke1985">{{cite journal|last1=Burke|first1=C.W.|title=Adrenocortical insufficiency|journal=Clinics in Endocrinology and Metabolism|volume=14|issue=4|year=1985|pages=947–976|issn=0300595X|doi=10.1016/S0300-595X(85)80084-0}}</ref><ref name="pmid25098712">{{cite journal| author=Bancos I, Hahner S, Tomlinson J, Arlt W| title=Diagnosis and management of adrenal insufficiency. | journal=Lancet Diabetes Endocrinol | year= 2015 | volume= 3 | issue= 3 | pages= 216-26 | pmid=25098712 | doi=10.1016/S2213-8587(14)70142-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25098712 }}</ref> | ||
* Nausea and vomiting | * Nausea and vomiting | ||
* Fatigue | * Fatigue | ||
* Abdominal pain | * Abdominal pain | ||
* Weight loss | * Weight loss | ||
* Chest pain | |||
* Confusion | |||
|- | |- | ||
|Growth Hormone (GH) | |Growth Hormone (GH) | ||
| | | | ||
* Short stature (In children) | |||
* Fatigue | * Fatigue | ||
* Decrease muscle mass | * Decrease muscle mass | ||
* Decrease bone mineral denisty which may lead to osteoporosis<ref name="pmid15001597">{{cite journal| author=Murray RD, Columb B, Adams JE, Shalet SM| title=Low bone mass is an infrequent feature of the adult growth hormone deficiency syndrome in middle-age adults and the elderly. | journal=J Clin Endocrinol Metab | year= 2004 | volume= 89 | issue= 3 | pages= 1124-30 | pmid=15001597 | doi=10.1210/jc.2003-030685 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15001597 }}</ref> | * Decrease bone mineral denisty which may lead to osteoporosis<ref name="pmid15001597">{{cite journal| author=Murray RD, Columb B, Adams JE, Shalet SM| title=Low bone mass is an infrequent feature of the adult growth hormone deficiency syndrome in middle-age adults and the elderly. | journal=J Clin Endocrinol Metab | year= 2004 | volume= 89 | issue= 3 | pages= 1124-30 | pmid=15001597 | doi=10.1210/jc.2003-030685 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15001597 }}</ref> | ||
|- | |- | ||
|Luteinizing Hormone (LH) | |Gonadotropin hormones: | ||
| | * Luteinizing Hormone (LH) | ||
* Follicle Stimulating Hormone (FSH) | |||
|In men: | |||
* Loss of libido | * Loss of libido | ||
* Sexual dysfunction | * Sexual dysfunction | ||
* Decrease bone mass | * Decrease bone mass | ||
* Decrease hair growth | * Decrease hair growth | ||
|- | In women:<ref name="pmid12050248">{{cite journal| author=Miller KK, Biller BM, Hier J, Arena E, Klibanski A| title=Androgens and bone density in women with hypopituitarism. | journal=J Clin Endocrinol Metab | year= 2002 | volume= 87 | issue= 6 | pages= 2770-6 | pmid=12050248 | doi=10.1210/jcem.87.6.8557 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12050248 }}</ref> | ||
| | * Amenorrhea | ||
| | * Oligomenorrhea | ||
* Amenorrhea | * Loss of libido | ||
* Oligomenorrhea | |||
* Loss of libido | |||
* Osteoporosis | * Osteoporosis | ||
|- | |- | ||
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* Weight gain | * Weight gain | ||
* Dry skin | * Dry skin | ||
|- | |||
|Prolactin | |||
| | |||
* Inability of postpartum lactation | |||
|- | |- | ||
| rowspan="2" |'''Posterior pituitary''' | | rowspan="2" |'''Posterior pituitary''' |
Revision as of 13:35, 11 July 2017
Hypopituitarism Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Hypopituitarism history and symptoms On the Web |
American Roentgen Ray Society Images of Hypopituitarism history and symptoms |
Risk calculators and risk factors for Hypopituitarism history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
History
Symptoms
History taking is important in cases of hypopituitarism as history of head trauma and brain injury increase the probability of diagnosing the disease. Patients of hypopituitarism may be asymptomatic or show symptoms which can be non specific or specific for the deficient hormone.[1]
Non specific symptoms
Patients of hypopituitarism may present with the following symptoms:
Acute hypopituitarism | Chronic hypopituitarism |
---|---|
|
Symptoms of deficient hormones
In hypopituitarism, either one of the pituitary gland hormones is decreased or the whole hormones are decreased in case of panhypopituitarism. In this table each hormone deficiency symptoms are listed.
Pituitary gland | Hormone | Symptoms of deficiency |
---|---|---|
Anterior pituitary | Adrenocorticotrophic Hormone (ACTH) | The most critical hormonal deficient in hypopituitarism.[2][3]
|
Growth Hormone (GH) |
| |
Gonadotropin hormones:
|
In men:
In women:[5]
| |
Thyroid Stimulating Hormone (TSH) |
| |
Prolactin |
| |
Posterior pituitary | Oxytocin |
|
Anti Diuretic Hormone (ADH |
|
References
- ↑ Ascoli, Paola; Cavagnini, Francesco (2006). "Hypopituitarism". Pituitary. 9 (4): 335–342. doi:10.1007/s11102-006-0416-5. ISSN 1386-341X.
- ↑ Burke, C.W. (1985). "Adrenocortical insufficiency". Clinics in Endocrinology and Metabolism. 14 (4): 947–976. doi:10.1016/S0300-595X(85)80084-0. ISSN 0300-595X.
- ↑ Bancos I, Hahner S, Tomlinson J, Arlt W (2015). "Diagnosis and management of adrenal insufficiency". Lancet Diabetes Endocrinol. 3 (3): 216–26. doi:10.1016/S2213-8587(14)70142-1. PMID 25098712.
- ↑ Murray RD, Columb B, Adams JE, Shalet SM (2004). "Low bone mass is an infrequent feature of the adult growth hormone deficiency syndrome in middle-age adults and the elderly". J Clin Endocrinol Metab. 89 (3): 1124–30. doi:10.1210/jc.2003-030685. PMID 15001597.
- ↑ Miller KK, Biller BM, Hier J, Arena E, Klibanski A (2002). "Androgens and bone density in women with hypopituitarism". J Clin Endocrinol Metab. 87 (6): 2770–6. doi:10.1210/jcem.87.6.8557. PMID 12050248.