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==Symptoms==
==Symptoms==
Hypoglycemic symptoms and manifestations can be divided into those produced by the counterregulatory hormones ([[adrenaline]] and [[glucagon]]) triggered by the falling glucose, and the neuroglycopenic effects produced by the reduced brain sugar.
* Hypoglycemic symptoms and manifestations can be divided into those produced by the counterregulatory hormones ([[adrenaline]] and [[glucagon]]) triggered by the falling glucose, and the neuroglycopenic effects produced by the reduced brain sugar.
* The attacks may occur in the fasting or postprandial state.
* Because of hypoglycemia unawareness, patients can't correct hypoglycemia themselves and need help from observer.  


the vast majority of episodes are reversed after the glucose level is raised to normal and the rare fatal episodes are generally thought to be the result of ventricular arrhythmia [15].
=== Adrenergic Manifestations <ref name="pmid8243825">{{cite journal| author=Towler DA, Havlin CE, Craft S, Cryer P| title=Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms. | journal=Diabetes | year= 1993 | volume= 42 | issue= 12 | pages= 1791-8 | pmid=8243825 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8243825  }}</ref> ===
 
they may occur in the fasting or postprandial state
 
because of hypoglycemia unawareness
 
Patients who have only sympathoadrenal symptoms (anxiety, weakness, tremor, perspiration, or palpitations), but normal concurrent plasma glucose concentrations, and resolution of symptoms after dietary modification have a low probability of having a hypoglycemic disorder. This combination is most common in patients with postprandial symptoms.
 
=== Adrenergic Manifestations [3,12,13] 14]. ===
*Shakiness, [[anxiety]], [[nervousness]], [[tremor]]
*Shakiness, [[anxiety]], [[nervousness]], [[tremor]]
*[[Palpitation]]s
*[[Palpitation]]s
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*[[Nausea]], [[vomit]]ing, [[abdominal pain|abdominal discomfort]]
*[[Nausea]], [[vomit]]ing, [[abdominal pain|abdominal discomfort]]


=== Neuroglycopenic Manifestations 12,13,15] ===
=== Neuroglycopenic Manifestations <ref name="pmid82438252">{{cite journal| author=Towler DA, Havlin CE, Craft S, Cryer P| title=Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms. | journal=Diabetes | year= 1993 | volume= 42 | issue= 12 | pages= 1791-8 | pmid=8243825 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8243825  }}</ref> ===
*Nonspecific [[dysphoria]], [[anxiety]], moodiness, [[depression]], crying
*Nonspecific [[dysphoria]], [[anxiety]], moodiness, [[depression]], crying
*Negativism, [[irritability]], belligerence, combativeness, rage
*Negativism, [[irritability]], belligerence, combativeness, rage

Revision as of 17:07, 13 July 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History

Symptoms

  • Hypoglycemic symptoms and manifestations can be divided into those produced by the counterregulatory hormones (adrenaline and glucagon) triggered by the falling glucose, and the neuroglycopenic effects produced by the reduced brain sugar.
  • The attacks may occur in the fasting or postprandial state.
  • Because of hypoglycemia unawareness, patients can't correct hypoglycemia themselves and need help from observer.

Adrenergic Manifestations [1]

Glucagon Manifestations

Neuroglycopenic Manifestations [2]

References

  1. Towler DA, Havlin CE, Craft S, Cryer P (1993). "Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms". Diabetes. 42 (12): 1791–8. PMID 8243825.
  2. Towler DA, Havlin CE, Craft S, Cryer P (1993). "Mechanism of awareness of hypoglycemia. Perception of neurogenic (predominantly cholinergic) rather than neuroglycopenic symptoms". Diabetes. 42 (12): 1791–8. PMID 8243825.


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