Gonadoblastoma: Difference between revisions

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   MeshID        = D018238 |
   MeshID        = D018238 |
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{{Gonadoblastoma}}
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==Overview==
==[[Gonadoblastoma overview|Overview]]==
A '''gonadoblastoma''' is a complex [[neoplasm]] composed of a mixture of [[gonad]]al elements, such as large primordial [[germ cell]]s, immature [[Sertoli cell]]s or [[granulosa cell]]s of the [[sex cord]], and gonadal [[stromal cell]]s.


==Associations==
==[[Gonadoblastoma historical perspective|Historical Perspective]]==
Gonadoblastoma is most often associated with abnormal chromosomal [[karyotype]], gonadal [[dysgenesis]], and the presence of a [[Y chromosome]].


It has been found in association with [[Turner's syndrome]].<ref name="pmid17947845">{{cite journal |author=Maggio MC, Liotta A, De Grazia E, Cimador M, Di Pace R, Corsello G |title=Polycystic ovary and gonadoblastoma in Turner's syndrome |journal=Minerva Pediatr. |volume=59 |issue=4 |pages=397–401 |year=2007 |pmid=17947845 |doi=}}</ref><ref name="pmid17128558">{{cite journal |author=Bianco B, Lipay MV, Melaragno MI, Guedes AD, Verreschi IT |title=Detection of hidden Y mosaicism in Turner's syndrome: importance in the prevention of gonadoblastoma |journal=J. Pediatr. Endocrinol. Metab. |volume=19 |issue=9 |pages=1113–7 |year=2006 |pmid=17128558 |doi=}}</ref>
==[[Gonadoblastoma pathophysiology|Pathophysiology]]==


==Classification==
==[[Gonadoblastoma epidemiology and demographics|Epidemiology & Demographics]]==
{{main|Germ cell tumor}}
Gonadoblastoma is classified as a [[germ cell tumor]].


Formerly, gonadoblastoma was sometimes regarded as a subset of [[dysgerminoma]]. In modern literature, it is sometimes considered to progress to dysgerminoma.<ref name="pmid17454768">{{cite journal |author=Cooper C, Cooper M, Carter J, Russell P |title=Gonadoblastoma progressing to dysgerminoma in a 55-year-old woman with normal karyotype |journal=Pathology |volume=39 |issue=2 |pages=284–5 |year=2007 |pmid=17454768 |doi=10.1080/00313020701230708}}</ref>
==[[Gonadoblastoma risk factors|Risk Factors]]==
 
==[[Gonadoblastoma screening|Screening]]==
 
==[[Gonadoblastoma causes|Causes of Gonadoblastoma]]==
 
==[[Gonadoblastoma differential diagnosis|Differentiating Gonadoblastoma from other Diseases]]==
 
==[[Gonadoblastoma natural history|Natural History, Complications & Prognosis]]==
 
==Diagnosis==
[[Gonadoblastoma history and symptoms|History & Symptoms]] | [[Gonadoblastoma physical examination|Physical Examination]] | [[Gonadoblastoma laboratory tests|Lab Tests]] | [[Gonadoblastoma electrocardiogram|Electrocardiogram]] | [[Gonadoblastoma chest x ray|Chest X Ray]] | [[Gonadoblastoma CT|CT]] | [[Gonadoblastoma MRI|MRI]] | [[Gonadoblastoma echocardiography or ultrasound|Echocardiography or Ultrasound]] | [[Gonadoblastoma other imaging findings|Other Imaging Findings]] | [[Gonadoblastoma other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Gonadoblastoma medical therapy|Medical Therapy]] | [[Gonadoblastoma surgery|Surgery]] | [[Gonadoblastoma primary prevention|Primary Prevention]] | [[Gonadoblastoma secondary prevention|Secondary Prevention]] | [[Gonadoblastoma cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Gonadoblastoma future or investigational therapies|Future or Investigational Therapies]]


==References==
==References==
{{reflist|2}}
{{reflist|2}}


==External links==
*[http://www.health.am/cr/testis-non-germ-cell-tumors/ www.health.am: Gonadoblastoma]
{{SIB}}
{{Tumors}}
{{Tumors}}
{{Soft tissue tumors and sarcomas}}
{{Soft tissue tumors and sarcomas}}

Revision as of 20:37, 18 January 2012

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Gonadoblastoma
ICD-O: M9073/1
MeSH D018238

Gonadoblastoma Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Gonadoblastoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

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MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

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Surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]

Overview

Historical Perspective

Pathophysiology

Epidemiology & Demographics

Risk Factors

Screening

Causes of Gonadoblastoma

Differentiating Gonadoblastoma from other Diseases

Natural History, Complications & Prognosis

Diagnosis

History & Symptoms | Physical Examination | Lab Tests | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

References

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