Gastroparesis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
There are no diagnostic laboratory findings associated with gastroparesis. However, some laboratory findings consistent with the diagnosis of gastroparesis and its complications include elevated [[blood urea nitrogen]] ([[BUN]]), [[creatinine]], [[erythrocyte sedimentation rate]] ([[ESR]]), or [[C-reactive protein]] ([[CRP]]). Elevated [[glucose]] or [[HbA1c|glycated hemoglobin levels (HbA1c)]] might be seen in patients with diabetic gastroparesis. | |||
[ | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
*There are no diagnostic laboratory findings associated with gastroparesis. | |||
*There are no diagnostic laboratory findings associated with | *Laboratory findings consistent with the diagnosis of gastroparesis and its complications include:<ref name="ParkmanYates2011">{{cite journal|last1=Parkman|first1=Henry P.|last2=Yates|first2=Katherine P.|last3=Hasler|first3=William L.|last4=Nguyan|first4=Linda|last5=Pasricha|first5=Pankaj J.|last6=Snape|first6=William J.|last7=Farrugia|first7=Gianrico|last8=Calles|first8=Jorge|last9=Koch|first9=Kenneth L.|last10=Abell|first10=Thomas L.|last11=McCallum|first11=Richard W.|last12=Petito|first12=Dorothy|last13=Parrish|first13=Carol Rees|last14=Duffy|first14=Frank|last15=Lee|first15=Linda|last16=Unalp–Arida|first16=Aynur|last17=Tonascia|first17=James|last18=Hamilton|first18=Frank|title=Dietary Intake and Nutritional Deficiencies in Patients With Diabetic or Idiopathic Gastroparesis|journal=Gastroenterology|volume=141|issue=2|year=2011|pages=486–498.e7|issn=00165085|doi=10.1053/j.gastro.2011.04.045}}</ref><ref name="PasrichaYates2015">{{cite journal|last1=Pasricha|first1=Pankaj J.|last2=Yates|first2=Katherine P.|last3=Nguyen|first3=Linda|last4=Clarke|first4=John|last5=Abell|first5=Thomas L.|last6=Farrugia|first6=Gianrico|last7=Hasler|first7=William L.|last8=Koch|first8=Kenneth L.|last9=Snape|first9=William J.|last10=McCallum|first10=Richard W.|last11=Sarosiek|first11=Irene|last12=Tonascia|first12=James|last13=Miriel|first13=Laura A.|last14=Lee|first14=Linda|last15=Hamilton|first15=Frank|last16=Parkman|first16=Henry P.|title=Outcomes and Factors Associated With Reduced Symptoms in Patients With Gastroparesis|journal=Gastroenterology|volume=149|issue=7|year=2015|pages=1762–1774.e4|issn=00165085|doi=10.1053/j.gastro.2015.08.008}}</ref><ref name="SteinEverhart2015">{{cite journal|last1=Stein|first1=Benjamin|last2=Everhart|first2=Kelly K.|last3=Lacy|first3=Brian E.|title=Gastroparesis|journal=Journal of Clinical Gastroenterology|volume=49|issue=7|year=2015|pages=550–558|issn=0192-0790|doi=10.1097/MCG.0000000000000320}}</ref> | ||
**Elevated [[Blood urea nitrogen|BUN]] in severe [[dehydration]] (normal [[Blood urea nitrogen|BUN]] <20 mg/dL) | |||
* | **Elevated [[creatinine]] in severe [[dehydration]] (normal [[creatinine]] <1.1 mg/dL for female, <1.2 mg/dL for male) | ||
*[ | **Elevated [[c-reactive protein]] (normal [[C-reactive protein|CRP]] <0.8 mg/dL) | ||
* | **Elevated [[erythrocyte sedimentation rate]] (normal [[Erythrocyte sedimentation rate|ESR]] <20 mm/h) | ||
**[ | **[[Hypoalbuminemia]] (normal [[albumin]] >3.5 g/dL) | ||
**[ | *Patients with gastroparesis might have abnormal tests depends on underlying cause:<ref name="ParkmanYates2011">{{cite journal|last1=Parkman|first1=Henry P.|last2=Yates|first2=Katherine|last3=Hasler|first3=William L.|last4=Nguyen|first4=Linda|last5=Pasricha|first5=Pankaj J.|last6=Snape|first6=William J.|last7=Farrugia|first7=Gianrico|last8=Koch|first8=Kenneth L.|last9=Calles|first9=Jorge|last10=Abell|first10=Thomas L.|last11=McCallum|first11=Richard W.|last12=Lee|first12=Linda|last13=Unalp–Arida|first13=Aynur|last14=Tonascia|first14=James|last15=Hamilton|first15=Frank|title=Similarities and Differences Between Diabetic and Idiopathic Gastroparesis|journal=Clinical Gastroenterology and Hepatology|volume=9|issue=12|year=2011|pages=1056–1064|issn=15423565|doi=10.1016/j.cgh.2011.08.013}}</ref> | ||
**[ | **Elevated [[Glycosylated hemoglobin|HbA1C]] (in diabetic gastroparesis) | ||
**Elevated [[glucose]] (in diabetic gastroparesis) | |||
* | **Elevated [[Thyroid-stimulating hormone|TSH]] in gastroparesis due to [[hypothyroidism]] (normal 0.4-5 mU/L)<ref name="pmid2860333">{{cite journal| author=Caldwell G, Kellett HA, Gow SM, Beckett GJ, Sweeting VM, Seth J et al.| title=A new strategy for thyroid function testing. | journal=Lancet | year= 1985 | volume= 1 | issue= 8438 | pages= 1117-9 | pmid=2860333 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2860333 }}</ref> | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Latest revision as of 16:03, 20 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2]
Overview
There are no diagnostic laboratory findings associated with gastroparesis. However, some laboratory findings consistent with the diagnosis of gastroparesis and its complications include elevated blood urea nitrogen (BUN), creatinine, erythrocyte sedimentation rate (ESR), or C-reactive protein (CRP). Elevated glucose or glycated hemoglobin levels (HbA1c) might be seen in patients with diabetic gastroparesis.
Laboratory Findings
- There are no diagnostic laboratory findings associated with gastroparesis.
- Laboratory findings consistent with the diagnosis of gastroparesis and its complications include:[1][2][3]
- Elevated BUN in severe dehydration (normal BUN <20 mg/dL)
- Elevated creatinine in severe dehydration (normal creatinine <1.1 mg/dL for female, <1.2 mg/dL for male)
- Elevated c-reactive protein (normal CRP <0.8 mg/dL)
- Elevated erythrocyte sedimentation rate (normal ESR <20 mm/h)
- Hypoalbuminemia (normal albumin >3.5 g/dL)
- Patients with gastroparesis might have abnormal tests depends on underlying cause:[1]
- Elevated HbA1C (in diabetic gastroparesis)
- Elevated glucose (in diabetic gastroparesis)
- Elevated TSH in gastroparesis due to hypothyroidism (normal 0.4-5 mU/L)[4]
References
- ↑ 1.0 1.1 Parkman, Henry P.; Yates, Katherine P.; Hasler, William L.; Nguyan, Linda; Pasricha, Pankaj J.; Snape, William J.; Farrugia, Gianrico; Calles, Jorge; Koch, Kenneth L.; Abell, Thomas L.; McCallum, Richard W.; Petito, Dorothy; Parrish, Carol Rees; Duffy, Frank; Lee, Linda; Unalp–Arida, Aynur; Tonascia, James; Hamilton, Frank (2011). "Dietary Intake and Nutritional Deficiencies in Patients With Diabetic or Idiopathic Gastroparesis". Gastroenterology. 141 (2): 486–498.e7. doi:10.1053/j.gastro.2011.04.045. ISSN 0016-5085.
- ↑ Pasricha, Pankaj J.; Yates, Katherine P.; Nguyen, Linda; Clarke, John; Abell, Thomas L.; Farrugia, Gianrico; Hasler, William L.; Koch, Kenneth L.; Snape, William J.; McCallum, Richard W.; Sarosiek, Irene; Tonascia, James; Miriel, Laura A.; Lee, Linda; Hamilton, Frank; Parkman, Henry P. (2015). "Outcomes and Factors Associated With Reduced Symptoms in Patients With Gastroparesis". Gastroenterology. 149 (7): 1762–1774.e4. doi:10.1053/j.gastro.2015.08.008. ISSN 0016-5085.
- ↑ Stein, Benjamin; Everhart, Kelly K.; Lacy, Brian E. (2015). "Gastroparesis". Journal of Clinical Gastroenterology. 49 (7): 550–558. doi:10.1097/MCG.0000000000000320. ISSN 0192-0790.
- ↑ Caldwell G, Kellett HA, Gow SM, Beckett GJ, Sweeting VM, Seth J; et al. (1985). "A new strategy for thyroid function testing". Lancet. 1 (8438): 1117–9. PMID 2860333.